Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities
The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …
Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives
A series of ten novel hydrazide–hydrazones linked indole and indazole moieties were
designed and synthesized. All the synthesized compounds were evaluated for their …
designed and synthesized. All the synthesized compounds were evaluated for their …
I 2-Promoted formal [3+ 2] cycloaddition of α-methylenyl isocyanides with methyl ketones: a route to 2, 5-disubstituted oxazoles
X Wu, X Geng, P Zhao, J Zhang, Y Wu… - Chemical …, 2017 - pubs.rsc.org
An I2-promoted formal [3+ 2] cycloaddition for access to oxazoles has been demonstrated.
This is the first example of a Lewis acid-promoted formal [3+ 2] cycloaddition of isocyanides …
This is the first example of a Lewis acid-promoted formal [3+ 2] cycloaddition of isocyanides …
A facile and microwave-assisted rapid synthesis of 2-arylamino-4-(3′-indolyl)-thiazoles as Apoptosis Inducing Cytotoxic Agents
Background and Objective: The clinical success of the chemotherapeutic drugs is restricted
by the nonspecific toxicity-related adverse side effects. The diverse implication of indoles …
by the nonspecific toxicity-related adverse side effects. The diverse implication of indoles …
Synthesis and antimicrobial activity of bis (azolyl) quinazoline-2, 4-diamines
T Rekha, S Durgamma, A Padmaja… - Monatshefte für Chemie …, 2017 - Springer
Some new bis (azolylamino)-and bis (azolylmethylamino) quinazolines were prepared from
2, 4-dichloroquinazoline and azolyl amines under ultrasonication and tested for their …
2, 4-dichloroquinazoline and azolyl amines under ultrasonication and tested for their …