Pancreatic cancer: molecular characterization, clonal evolution and cancer stem cells

E Pelosi, G Castelli, U Testa - Biomedicines, 2017 - mdpi.com
Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-
related death and is the most lethal of common malignancies with a five-year survival rate …

Challenges in using ctDNA to achieve early detection of cancer

IS Haque, O Elemento - BioRxiv, 2017 - biorxiv.org
Early detection of cancer is a significant unmet clinical need. Improved technical ability to
detect circulating tumor-derived DNA (ctDNA) in the cell-free DNA (cfDNA) component of …

[HTML][HTML] Can circulating tumor DNA be used for direct and early stage cancer detection?

EP Diamandis, C Fiala - F1000Research, 2017 - ncbi.nlm.nih.gov
In the August 16th issue of Science Translational Medicine, Phallen et al propose a method
for early cancer diagnosis by using circulating tumor DNA (1). One major advance of this …

Can circulating tumor DNA be used for direct and early stage cancer detection?[version 1; referees: 2 approved]

EP Diamandis, C Fiala - 2017 - europepmc.org
In the August 16th issue of Science Translational Medicine, Phallen et al propose a method
for early cancer diagnosis by using circulating tumor DNA (1). One major advance of this …

Aspect pré analytique et intérêt clinique de la détection d'ADN tumoral circulant par PCR digitale en oncologie digestive

D Sefrioui - 2017 - theses.hal.science
L'ADN tumoral circulant (ADNtumc) est apparu depuis plusieurs années comme un
biomarqueur prometteur susceptible d'apporter des informations permettant l'optimisation de …

液体生検(Liquid biopsy)

市川大輔 - 日本外科系連合学会誌, 2017 - jstage.jst.go.jp
以前より血液中に遊離核酸断片が存在することが知られていた 1). この血液中遊離核酸が採血
のみの非侵襲的手法によって採取が可能であることや, 検診などのスクリーニング手法として期待 …