Restoration of blood flow to myocardium previously subjected to ischemia leads to
ischemia/reperfusion injury due to oxidative stress. An increased production of toxic …

Chronic hypoxia exacerbates proliferation of pulmonary arterial smooth muscle cells
(PASMC), thereby reducing the lumen of pulmonary arteries. This leads to poor blood …

Astaxanthin (AST) is a carotenoid that has been shown to have neuroprotective effects. In
this study, it was found that AST significantly inhibited glutamate-induced loss of cell viability …

Rationale Heart failure is a multimodal disorder, of which disrupted Ca 2+ homeostasis is a
hallmark. Central to Ca 2+ homeostasis is the major cardiac Ca 2+ release channel–the …

Гибель кардиомиоцитов при ишемическом и реперфузионном повреждении миокарда
по современным представлениям может происходить не только спонтанно, но и путем …

It has now been well established that different mitochondrial compartments contain varieties
of calpains. The expression levels of these calpains are tissue and cell type specific …

Chronic hypoxia exacerbates proliferation of pulmonary arterial smooth muscle cells
(PASMC), thereby reducing the lumen of pulmonary arteries. This leads to poor blood …

Maintaining the equilibrium between saturated and unsaturated fatty acids within membrane
phospholipids (PLs) is crucial to sustain the optimal membrane biophysical properties …

Lung cancer is considered as one of the most important causes of cancer-related death
worldwide and Non-Small Cell Lung Cancer (NSCLC) accounts for 80% of all lung cancer …

Human cardiac ryanodine receptors (hRyR2) are calcium (Ca2+) release channels central
to excitation-contraction coupling. Mutations in hRyR2 are linked to catecholaminergic …