Cardiovascular pharmacogenetics: a promise for genomically‐guided therapy and personalized medicine
M Zaiou, H El Amri - Clinical genetics, 2017 - Wiley Online Library
Cardiovascular disease (CVD) is the leading cause of death worldwide. The basic causes of
CVD are not fully understood yet. Substantial evidence suggests that genetic predisposition …
CVD are not fully understood yet. Substantial evidence suggests that genetic predisposition …
Genetic signatures in ischemic stroke: focus on aspirin resistance
K Vasudeva, P Chaurasia, S Singh… - CNS & Neurological …, 2017 - ingentaconnect.com
Background and Objective: Stroke is one of the leading causes of death. There has been
compelling evidence that stroke has a genetic component. Genetic variants not only …
compelling evidence that stroke has a genetic component. Genetic variants not only …
Genetic variants of PTGS2, TXA2R and TXAS1 are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients
X Yi, J Lin, H Luo, C Wang, Y Liu - PLoS One, 2017 - journals.plos.org
Eicosanoids may play a role in ischemic stroke. However, the associations of variants in
cyclooxygenase (COX) pathway genes and interaction among these variants with carotid …
cyclooxygenase (COX) pathway genes and interaction among these variants with carotid …
Recent developments and future directions for the use of pharmacogenomics in cardiovascular disease treatments
E Berinstein, A Levy - Expert opinion on drug metabolism & …, 2017 - Taylor & Francis
Introduction: Cardiovascular disease is still the leading cause of death worldwide. There are
many environmental and genetic factors that play a role in the development of …
many environmental and genetic factors that play a role in the development of …
Variants in COX-2, PTGIS, and TBXAS1 are associated with carotid artery or intracranial arterial stenosis and neurologic deterioration in ischemic stroke patients
X Yi, B Ming, C Wang, H Chen, C Ma - Journal of Stroke and …, 2017 - Elsevier
Background Eicosanoids may play a role in ischemic stroke (IS). However, the association of
variants in eicosanoid genes with symptomatic carotid artery or intracranial arterial stenosis …
variants in eicosanoid genes with symptomatic carotid artery or intracranial arterial stenosis …
Association of frequent genetic variants in platelet activation pathway genes with large-vessel ischemic stroke in Polish population
Platelets are critically involved in the development of cerebral ischemia. Our study aimed to
establish an association between frequent (minor allele frequency (MAF)> 5%) genetic …
establish an association between frequent (minor allele frequency (MAF)> 5%) genetic …
Interactions among variants in eicosanoid genes increase risk of atherothrombotic stroke in Chinese populations
X Yi, J Lin, C Wang, R Huang, Y Liu - Journal of Stroke and …, 2017 - Elsevier
Background Eicosanoids are lipid mediators that may play a role in ischemic stroke (IS).
However, the association of variants in eicosanoid genes and these interactions with IS risk …
However, the association of variants in eicosanoid genes and these interactions with IS risk …
Influcencia de los polimorfismos de ciclooxigenasa-2 en el desarrollo del adenocarcinoma gástrico en Aragón
MA García González, E Piazuelo Ortega - zaguan.unizar.es
Introducción: La Ciclooxigenasa 2 (Cox-2) es una enzima que interviene en la conversión
del ácido araquidónico a prostaglandinas las cuales son importantes mediadores de la …
del ácido araquidónico a prostaglandinas las cuales son importantes mediadores de la …
[PDF][PDF] INFLUENCIA DE LOS POLIMORFISMOS DE CICLOOXIGENASA-2 EN EL DESARROLLO DEL ADENOCARCINOMA GÁSTRICO EN ARAGÓN. INFLUENCE …
AB Arguiñena, MAG González, EP Ortega - core.ac.uk
Introducción: La Ciclooxigenasa 2 (Cox-2) es una enzima que interviene en la conversión
del ácido araquidónico a prostaglandinas las cuales son importantes mediadores de la …
del ácido araquidónico a prostaglandinas las cuales son importantes mediadores de la …
[PDF][PDF] General Features of Endophenotype
J Vonk, TK Shackelford - 2017 - researchgate.net
2. Endophenotype and illness (appearance of a disorder) co-segregate within families. 3.
The endophenotype is primarily state independent (always appears in an individual …
The endophenotype is primarily state independent (always appears in an individual …