The role of aquaporins in ocular lens homeostasis

KL Schey, RS Petrova, RB Gletten… - International journal of …, 2017 - mdpi.com
Aquaporins (AQPs), by playing essential roles in the maintenance of ocular lens
homeostasis, contribute to the establishment and maintenance of the overall optical …

[HTML][HTML] N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis

CM Logan, S Rajakaruna, C Bowen, GL Radice… - Developmental …, 2017 - Elsevier
Tissue development and regeneration involve high-ordered morphogenetic processes that
are governed by elements of the cytoskeleton in conjunction with cell adhesion molecules …

Induction of immune surveillance of the dysmorphogenic lens

CM Logan, CJ Bowen, AS Menko - Scientific reports, 2017 - nature.com
The lens has been considered to be an immune privileged site not susceptible to the
immune processes normally associated with tissue injury and wound repair. However, as …

Aquaporin 0 modulates lens gap junctions in the presence of lens-specific beaded filament proteins

S Kumari, J Gao, RT Mathias, X Sun… - … & Visual Science, 2017 - iovs.arvojournals.org
Purpose: The objective of this study was to understand the molecular and physiologic
mechanisms behind the lens cataract differences in Aquaporin 0-knockout-Heterozygous …

Connexin 50 functions as an adhesive molecule and promotes lens cell differentiation

Z Hu, W Shi, MA Riquelme, Q Shi, S Biswas, WK Lo… - Scientific reports, 2017 - nature.com
Connexins play essential roles in lens homeostasis and development. Here, we identified a
new role for Cx50 that mediates cell-cell adhesion function. Cx50 enhanced the adhesive …

Identification of a direct Aquaporin-0 binding site in the lens-specific cytoskeletal protein filensin

Z Wang, KL Schey - Experimental eye research, 2017 - Elsevier
An interaction between the C-terminus of aquaporin-0 (AQP0) and lens beaded filament
protein filensin has been reported previously; however, the region of filensin that is involved …

The extracellular C-loop domain plays an important role in the cell adhesion function of aquaporin 0

Y Nakazawa, M Oka, M Funakoshi-Tago… - Current Eye …, 2017 - Taylor & Francis
ABSTRACT Purpose: Although aquaporin 0 (AQP0) is a member of the AQP family, it has
limited water permeability compared with other members. AQP0 may also have cell …