Neutrophil extracellular traps and its implications in inflammation: an overview

V Delgado-Rizo, MA Martínez-Guzmán… - Frontiers in …, 2017 - frontiersin.org
In addition to physical barriers, neutrophils are considered a part of the first line of immune
defense. They can be found in the bloodstream, with a lifespan of 6–8 h, and in tissue …

Aspergillus fumigatus morphology and dynamic host interactions

FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

The Cell Wall of the Human Fungal Pathogen Aspergillus fumigatus: Biosynthesis, Organization, Immune Response, and Virulence

JP Latgé, A Beauvais, G Chamilos - Annual review of …, 2017 - annualreviews.org
More than 90% of the cell wall of the filamentous fungus Aspergillus fumigatus comprises
polysaccharides. Biosynthesis of the cell wall polysaccharides is under the control of three …

[HTML][HTML] Immunity against fungi

MS Lionakis, ID Iliev, TM Hohl - JCI insight, 2017 - ncbi.nlm.nih.gov
Pathogenic fungi cause a wide range of syndromes in immune-competent and immune-
compromised individuals, with life-threatening disease primarily seen in humans with …

Immune recognition of fungal polysaccharides

BD Snarr, ST Qureshi, DC Sheppard - Journal of fungi, 2017 - mdpi.com
The incidence of fungal infections has dramatically increased in recent years, in large part
due to increased use of immunosuppressive medications, as well as aggressive medical …

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity

BD Snarr, P Baker, NC Bamford… - Proceedings of the …, 2017 - National Acad Sciences
Galactosaminogalactan and Pel are cationic heteropolysaccharides produced by the
opportunistic pathogens Aspergillus fumigatus and Pseudomonas aeruginosa, respectively …

Mechanisms involved in the triggering of neutrophil extracellular traps (NETs) by Candida glabrata during planktonic and biofilm growth

CJ Johnson, JF Kernien, AR Hoyer, JE Nett - Scientific Reports, 2017 - nature.com
Candida spp. adhere to medical devices, such as catheters, forming drug-tolerant biofilms
that resist killing by the immune system. Little is known about how C. glabrata, an emerging …

Streptococcus suis Serotype 2 Biofilms Inhibit the Formation of Neutrophil Extracellular Traps

F Ma, L Yi, N Yu, G Wang, Z Ma, H Lin… - Frontiers in cellular and …, 2017 - frontiersin.org
Invasive infections caused by Streptococcus suis serotype 2 (SS2) has emerged as a clinical
problem in recent years. Neutrophil extracellular traps (NETs) are an important mechanism …

Immune responses to invasive aspergillosis: new understanding and therapeutic opportunities

TM Hohl - Current opinion in infectious diseases, 2017 - journals.lww.com
Immune responses to invasive aspergillosis: new understandin... : Current Opinion in Infectious
Diseases Immune responses to invasive aspergillosis: new understanding and therapeutic …

Posaconazole-loaded leukocytes as a novel treatment strategy targeting invasive pulmonary aspergillosis

SR Baistrocchi, MJ Lee, M Lehoux… - The Journal of …, 2017 - academic.oup.com
Background Impaired delivery of antifungals to hyphae within necrotic lesions is thought to
contribute to therapeutic failure in invasive pulmonary aspergillosis (IPA). We hypothesized …