Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

To curb the high cost of drug development, there is an urgent need to develop more
predictive tissue models using human cells to determine drug efficacy and safety in advance …

Many drugs have progressed through preclinical and clinical trials and have been available–
for years in some cases–before being recalled by the FDA for unanticipated toxicity in …

The linear growth of operators in local quantum systems leads to an effective light cone even
if the system is nonrelativistic. We show that the consistency of diffusive transport with this …

This study demonstrates a new strategy for the development of a three-dimensional (3D) cell
culture model-based cellular biosensing system. Distinctly different from the previously …

In the last few years, considerable attention has been given to in vitro models in an attempt
to reduce the use of animals and to decrease the rate of preclinical failure associated with …

In recent years, 3D integrated microfluidic systems have become increasingly more popular
because of their ability to incorporate multifunctional components, including porous …

Continuous and long-term monitoring of cellular and micro-organ activity is required for new
insights into physiology and novel technologies such as Organs-on-Chip. Moreover, recent …

Organs-on-Chips (OoCs) are poised to reshape dramatically the study of biology by
replicating in vivo the function of individual and coupled human organs. Such …

Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease, affecting over 10 million individuals worldwide. While numerous …