Abstract The Wiskott–Aldrich syndrome protein (WASP) participates in innate and adaptive
immunity through regulation of actin cytoskeleton‐dependent cellular processes, including …

Few monogenic causes for severe manifestations of common allergic diseases have been
identified. Through next-generation sequencing on a cohort of patients with severe atopic …

Abstract Human actin-related protein 2/3 complex (Arp2/3), required for actin filament
branching, has two ARPC1 component isoforms, with ARPC1B prominently expressed in …

Nonimmunological connective tissue phenotypes in humans are common among some
congenital and acquired allergic diseases. Several of these congenital disorders have been …

Homeostasis in the gastrointestinal tract relies on a sensitive equilibrium between
permissive and protective functions. This is closely reflected in the regulation of the intestinal …

Natural and artificial animal models were used to explore the pathophysiology of asthma,
food allergy and anaphylaxis and to improve prophylactic and therapeutic measures …

Background Food allergies are a growing health problem, and the development of therapies
that prevent disease onset is limited by the lack of adjuvant‐free experimental animal …

Outstanding animal studies in allergy II. From atopic barrie... : Current Opinion in Allergy and
Clinical Immunology Outstanding animal studies in allergy II. From atopic barrier and microbiome …

摘要目的: 探讨肝癌患者外周血和癌组织中CD8+CD28-Foxp3+ 调节性T 细胞(CD8+CD28-
Foxp3+Tregs) 的改变及意义. 方法: 采用流式细胞仪检测72 例肝癌患者和22 …

Abstract Wiskott-Aldrich Syndrome (WAS) is a primary immunodeficiency caused by
mutation in the WAS gene, resulting in reduced or absent expression of WAS protein …