Studies on the Caenorhabditis elegans nucleus have provided fascinating insight to the
organization and activities of eukaryotic cells. Being the organelle that holds the genetic …

Although the zebrafish was initially developed as a model system to study embryonic
development, it has gained increasing attention as an advantageous system to investigate …

DNA damage causally contributes to aging and age-related diseases. Mutations in
nucleotide excision repair (NER) genes cause highly complex congenital syndromes …

Piwi in a complex with Piwi-interacting RNAs (piRNAs) triggers transcriptional silencing of
transposable elements (TEs) in Drosophila ovaries, thus ensuring genome stability. To do …

Upon fertilisation, the sperm pronucleus acquires the competence to replicate the genome
through a cascade of events that link chromatin remodelling to nuclear envelope formation …