Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a
healthcare burden of epidemic proportions for which there is currently no cure …

Background No large trials have been done to investigate the efficacy of an intervention
combining a specific compound and several lifestyle interventions compared with placebo …

Brain cells normally respond adaptively to bioenergetic challenges resulting from ongoing
activity in neuronal circuits, and from environmental energetic stressors such as food …

Basic research advances in recent years have furthered our understanding of the natural
history of Alzheimer's disease (AD). It is now recognized that pathophysiological changes …

The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers …

Cognitive function is an important component of aging and predicts quality of life, functional
independence, and risk of institutionalization. Advances in our understanding of the role of …

The current literature includes several studies investigating the association between
physical activity and risk of Alzheimer's disease (AD). The aim of this review was to …