Adiponectin is the most abundant peptide secreted by adipocytes, whose reduction plays a
central role in obesity-related diseases, including insulin resistance/type 2 diabetes and …

Epidemiologic and clinical data from the last 2 decades have shown that the prevalence of
heart failure in diabetes is very high, and the prognosis for patients with heart failure is …

Heart failure is a global public health problem that affects more than 26 million people
worldwide. The global burden of heart failure is growing and is expected to increase …

Nowadays, obesity is seriously increasing in most of the populations all over the world, and
is associated with the development and progression of high-mortality diseases such as type …

Background and aims Pioglitazone targets multiple pathogenic pathways involved in the
development of cardiovascular diseases (CVD). The aim of this systematic review and meta …

Recently, treatment with 2 newer classes of type 2 diabetes drugs were found to reduce
events in patients with diabetes and cardiovascular (CV) disease, a group common in …

The preferential solvation parameters (δx 1, 3) of pioglitazone hydrochloride in four binary
solvent mixtures of {ethanol (1)+ water (2)},{N-methyl pyrrolidone (NMP)(1)+ water …

Patients with type 2 diabetes mellitus have a twofold increased risk of cardiovascular
mortality compared with non-diabetic individuals. There is a growing awareness that …

Insulin resistance is the undisputed root cause of type 2 diabetes mellitus (T2DM). There is
currently an unmet demand for safe and effective insulin sensitizers, owing to the restricted …

De acuerdo con su mecanismo de acción, existen cinco grupos principales de
hipoglucemiantes orales para el tratamiento de la diabetes mellitus tipo 2: secretagogos de …