Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

The antiphospholipid syndrome in patients with systemic lupus erythematosus

GJ Pons-Estel, L Andreoli, F Scanzi, R Cervera… - Journal of …, 2017 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
occurrence of venous and/or arterial thrombosis and pregnancy morbidity in the presence of …

Antiphospholipid syndrome

R Cervera - Thrombosis research, 2017 - Elsevier
The antiphospholipid syndrome (APS) is defined by the development of venous and/or
arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses) …

Antiphospholipid syndrome: role of vascular endothelial cells and implications for risk stratification and targeted therapeutics

MT Corban, A Duarte-Garcia, RD McBane… - Journal of the American …, 2017 - jacc.org
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …

Long-term use of hydroxychloroquine reduces antiphospholipid antibodies levels in patients with primary antiphospholipid syndrome

E Nuri, M Taraborelli, L Andreoli, M Tonello… - Immunologic …, 2017 - Springer
Hydroxychloroquine (HCQ) was suggested to play a role in lowering antiphospholipid
antibody titers and preventing thrombotic recurrences in patients with systemic lupus …

Diagnosis and management of the antiphospholipid syndrome

S Chaturvedi, KR McCrae - Blood reviews, 2017 - Elsevier
Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory …

[HTML][HTML] The role of toll-like receptor 4 in tumor microenvironment

J Li, F Yang, F Wei, X Ren - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumors are closely related to chronic inflammation, during which there are various changes
in inflammatory sites, such as immune cells infiltration, pro-inflammation cytokines …

Longterm outcome of patients with primary antiphospholipid syndrome: a retrospective multicenter study

M Taraborelli, R Reggia, F Dall'Ara, M Fredi… - The Journal of …, 2017 - jrheum.org
Objective. To assess the longterm frequency of thrombotic recurrences, obstetrical
complications, organ damage, severe comorbidities, and evolution toward connective tissue …

The adjusted Global AntiphosPholipid Syndrome Score (aGAPSS) for risk stratification in young APS patients with acute myocardial infarction

M Radin, K Schreiber, P Costanzo, I Cecchi… - International journal of …, 2017 - Elsevier
Background Young adults with acute myocardial infarction are a critical group to examine for
the purpose of risk factor stratification and modification. In this study we aimed to assess the …

Current insights in obstetric antiphospholipid syndrome

K Schreiber, M Radin, S Sciascia - Current Opinion in Obstetrics …, 2017 - journals.lww.com
APS is among the most frequent acquired risk factors for a treatable cause of recurrent
pregnancy loss and increases the risk of conditions associated with ischaemic placental …