This is the second part of a three-part review series reviewing the most important advances
in Alzheimer's disease (AD) research since 2010. This review covers the latest research on …

The field of Alzheimer disease (AD) prevention has been a culmination of basic science,
clinical, and translational research. In the past three years since the new 2011 AD diagnostic …

Alzheimer's disease (AD) is a large and growing public health problem. It is characterized by
the accumulation of amyloid-β peptides and abnormally phosphorylated tau proteins that are …

Few data are available concerning the role of risk markers for Alzheimer's disease (AD) in
progression to AD dementia among subjects with mild cognitive impairment (MCI). We …

Mitochondrial and bioenergetic function change with advancing age and may drive aging
phenotypes. Mitochondrial and bioenergetic changes are also documented in various age …

Alzheimer disease (AD) was originally conceived as a rare disease that caused presenile
dementia but has come to be understood as the most prevalent cause of dementia at any …

The last decade has witnessed a proliferation of neuroimaging studies characterising brain
changes associated with Alzheimer's disease (AD), where both widespread atrophy and …

It is hypothesized that retrotransposons have played a fundamental role in primate evolution
and that enhanced neurologic retrotransposon activity in humans may underlie the origin of …

Background Vascular dementia is a common disorder resulting in considerable morbidity
and mortality. Determining the extent to which genes play a role in disease susceptibility and …

A variable-length poly-T variant in intron 6 of the TOMM40 gene, rs10524523, is associated
with risk and age-of-onset of sporadic (late-onset) Alzheimer's disease. In Caucasians, the …