Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). The
activation of inflammatory cells is crucial for the development of MS and is shown to induce …

Our lab has previously demonstrated that multiple sclerosis-induced spinal cord white matter
damage and motor deficits are mediated by the pathological disruption of zinc homeostasis …

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are
inflammatory diseases of the central nervous system. Although several studies have …

The aim of this study was to investigate the effects of interferon (IFN)-β1a and IFN-β1b
treatment on inflammatory factors and myelin protein levels in the brain cortex of the Lewis …

Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS).
Axonal degeneration, one of the main pathological characteristics of MS, is affected by nitric …

Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous
system. Only a few biomarkers are available in MS clinical practice, such as cerebrospinal …

Post-translational modifications of autoantigens are hypothesized to affect their
immunogenicity. We here report that nitration of tyrosine 40 in Myelin Oligodendrocyte …

Introduction. Glycation is a post-translational modification of proteins that depends on the
non-enzymatic linkage of a ketone or aldehyde group of sugar with a free amino group of …

Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by
neuromuscular junction decay, motor neuron death, progressive paralysis, and eventually …

Protein tyrosine nitration (PTN) is a post translational event which results in the generation of
3-Nitrotyrosine (3-NT). High levels of 3-NT were reported in several human diseases such …