Head and neck cancer: improving outcomes with a multidisciplinary approach

C Lo Nigro, N Denaro, A Merlotti… - Cancer management and …, 2017 - Taylor & Francis
For early-stage head and neck cancer (HNC), surgery (S) or radiotherapy (RT) is a standard
treatment. The multidisciplinary approach, which includes multimodality treatment with S …

Weekly low‐dose versus three‐weekly high‐dose cisplatin for concurrent chemoradiation in locoregionally advanced non‐nasopharyngeal head and neck cancer: a …

P Szturz, K Wouters, N Kiyota, M Tahara… - The …, 2017 - academic.oup.com
Background Three‐weekly high‐dose cisplatin (100 mg/m2) is considered the standard
systemic regimen given concurrently with postoperative or definitive radiotherapy in locally …

Long-term survival of a randomized phase III trial of head and neck cancer patients receiving concurrent chemoradiation therapy with or without low-level laser therapy …

HS Antunes, D Herchenhorn, IA Small, CMM Araújo… - Oral oncology, 2017 - Elsevier
Background The impact of low-level laser therapy (LLLT) to prevent oral mucositis in
patients treated with exclusive chemoradiation therapy remains unknown. This study …

Free-circulating methylated DNA in blood for diagnosis, staging, prognosis, and monitoring of head and neck squamous cell carcinoma patients: an observational …

A Schröck, A Leisse, L de Vos, H Gevensleben… - Clinical …, 2017 - academic.oup.com
BACKGROUND Circulating cell-free DNA methylation testing in blood has recently received
regulatory approval for screening of colorectal cancer. Its application in other clinical …

Effect of particle size on the biodistribution, toxicity, and efficacy of drug-loaded polymeric nanoparticles in chemoradiotherapy

JM Caster, KY Stephanie, AN Patel, NJ Newman… - … , Biology and Medicine, 2017 - Elsevier
Nanoparticle (NP) chemotherapeutics can improve the therapeutic index of
chemoradiotherapy (CRT). However, the effect of NP physical properties, such particle size …

[HTML][HTML] Immunotherapy in head and neck cancer: aiming at EXTREME precision

P Szturz, JB Vermorken - BMC medicine, 2017 - Springer
Background Locoregionally advanced, recurrent, and metastatic squamous cell carcinomas
of the head and neck (SCCHN) remain difficult to treat disease entities, in which systemic …

Long-term toxicities in 10-year survivors of radiation treatment for head and neck cancer

Y Dong, JA Ridge, T Li, MN Lango, TM Churilla… - Oral oncology, 2017 - Elsevier
Objectives To characterize the recognized but poorly understood long-term toxicities of
radiation therapy (RT) for head and neck cancer (HNC). Materials and methods We …

The role of human papillomavirus on the prognosis and treatment of oropharyngeal carcinoma

N Fung, F Faraji, H Kang, C Fakhry - Cancer and Metastasis Reviews, 2017 - Springer
Human papillomavirus positive oropharyngeal cancer (HPV-positive OPC) is a distinct
subtype of head and neck carcinoma (HNC) distinguished from HPV-negative HNC by its …

Immunotherapy of head and neck cancer: emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting

JE Bauman, E Cohen, RL Ferris, DJ Adelstein… - Cancer, 2017 - Wiley Online Library
Recent advances have permitted successful therapeutic targeting of the immune system in
head and neck squamous cell carcinoma (HNSCC). These new immunotherapeutic targets …

[HTML][HTML] Primary concurrent chemoradiation in head and neck cancers with weekly cisplatin chemotherapy: analysis of compliance, toxicity and survival

MS Iqbal, C Chaw, J Kovarik, S Aslam… - International …, 2017 - thieme-connect.com
Introduction Concurrent chemoradiation is the standard of care in inoperable locally
advanced squamous cell head and neck cancers. The most widely accepted schedule of …