[HTML][HTML] Translational cardiac stem cell therapy: advancing from first-generation to next-generation cell types
E Cambria, FS Pasqualini, P Wolint, J Günter… - NPJ Regenerative …, 2017 - nature.com
Acute myocardial infarction and chronic heart failure rank among the major causes of
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …
morbidity and mortality worldwide. Except for heart transplantation, current therapy options …
Safety and efficacy of the intravenous infusion of umbilical cord mesenchymal stem cells in patients with heart failure: a phase 1/2 randomized controlled trial …
J Bartolucci, FJ Verdugo, PL González… - Circulation …, 2017 - Am Heart Assoc
Rationale: Umbilical cord–derived mesenchymal stem cells (UC-MSC) are easily accessible
and expanded in vitro, possess distinct properties, and improve myocardial remodeling and …
and expanded in vitro, possess distinct properties, and improve myocardial remodeling and …
Mesenchymal stem cells as a source of dopaminergic neurons: a potential cell based therapy for Parkinson's disease
K Venkatesh, D Sen - Current Stem Cell Research & Therapy, 2017 - ingentaconnect.com
Cell repair/replacing strategies for neurodegenerative diseases such as Parkinson's disease
depend on well-characterized dopaminergic neuronal candidates that are healthy and show …
depend on well-characterized dopaminergic neuronal candidates that are healthy and show …
Enhanced cardioprotection by human endometrium mesenchymal stem cells driven by exosomal microRNA-21
K Wang, Z Jiang, KA Webster, J Chen… - Stem cells …, 2017 - academic.oup.com
Our group recently reported positive therapeutic benefit of human endometrium-derived
mesenchymal stem cells (EnMSCs) delivered to infarcted rat myocardium, an effect that …
mesenchymal stem cells (EnMSCs) delivered to infarcted rat myocardium, an effect that …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury
Objective Preterm brain injury is a major cause of disability in later life, and may result in
motor, cognitive and behavioural impairment for which no treatment is currently available …
motor, cognitive and behavioural impairment for which no treatment is currently available …
[HTML][HTML] Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction
While the studies on the material interaction with mesenchymal stem cells (MSCs) have
been mainly focused on the ability of materials to provide environment to regulate cell …
been mainly focused on the ability of materials to provide environment to regulate cell …
Exosomes derived from human umbilical cord mesenchymal stem cells relieve inflammatory bowel disease in mice
F Mao, Y Wu, X Tang, J Kang, B Zhang… - BioMed research …, 2017 - Wiley Online Library
Exosomes secreted by mesenchymal stem cells (MSCs) have shown repairing effects on
several tissue injury diseases. In this study, we aimed to investigate the effects of exosomes …
several tissue injury diseases. In this study, we aimed to investigate the effects of exosomes …
Route of delivery modulates the efficacy of mesenchymal stem cell therapy for myocardial infarction: a meta-analysis of preclinical studies and clinical trials
AJ Kanelidis, C Premer, J Lopez, W Balkan… - Circulation …, 2017 - Am Heart Assoc
Rationale: Accumulating data support a therapeutic role for mesenchymal stem cell (MSC)
therapy; however, there is no consensus on the optimal route of delivery. Objective: We …
therapy; however, there is no consensus on the optimal route of delivery. Objective: We …
Paracrine effects of the pluripotent stem cell-derived cardiac myocytes salvage the injured myocardium
A Tachibana, MR Santoso, M Mahmoudi… - Circulation …, 2017 - Am Heart Assoc
Rationale: Cardiac myocytes derived from pluripotent stem cells have demonstrated the
potential to mitigate damage of the infarcted myocardium and improve left ventricular …
potential to mitigate damage of the infarcted myocardium and improve left ventricular …
A deep proteome analysis identifies the complete secretome as the functional unit of human cardiac progenitor cells
Rationale: Cardiac progenitor cells are an attractive cell type for tissue regeneration, but
their mechanism for myocardial remodeling is still unclear. Objective: This investigation …
their mechanism for myocardial remodeling is still unclear. Objective: This investigation …