The 3D structure of human DP prostaglandin G-protein-coupled receptor bound to Cyclopentanoindole antagonist, predicted using the DuplexBiHelix modification of …

V Shankar, WA Goddard III, SK Kim… - Journal of Chemical …, 2017 - ACS Publications
Prostaglandins play a critical physiological role in both cardiovascular and immune systems,
acting through their interactions with 9 prostanoid G protein-coupled receptors (GPCRs) …

Identifying multiple active conformations in the G protein-coupled receptor activation landscape using computational methods

SS Dong, WA Goddard III, R Abrol - Methods in cell biology, 2017 - Elsevier
G protein-coupled receptors (GPCRs) are membrane proteins critical in cellular signaling,
making them important targets for therapeutics. The activation of GPCRs is central to their …

[PDF][PDF] Virtual Screening, Pharmacophore Modeling, and Quantitative Structure Activity Relationship Studies on Histamine 4 Receptor

S Shobana - Asian J. Pharm. Clin. Res, 2017 - core.ac.uk
Objective: To find out novel inhibitors for histamine 4 receptor (H4R), the target for various
allergic and inflammatory pathophysiological conditions. Methods: Homology modeling of …

[PDF][PDF] The 3D Structure of Human DP Prostaglandin G Protein-Coupled Receptor Bound to CPI Antagonist, predicted using the DuplexBiHelix modification of the …

F Liu - authors.library.caltech.edu
The Predicted 3D Structure of Human DP Prostaglandin G Protein-Coupled Receptor Bound to
CPI Antagonist Page 1 Subscriber access provided by Caltech Library Journal of Chemical …