The role of chemokines in thyroid carcinoma
S Yapa, O Mulla, V Green, J England, J Greenman - Thyroid, 2017 - liebertpub.com
The global incidence of thyroid cancer is increasing, and metastatic spread to the lymph
nodes is common in papillary thyroid carcinoma. The metastatic course of thyroid carcinoma …
nodes is common in papillary thyroid carcinoma. The metastatic course of thyroid carcinoma …
Cancer stem cell and its niche in malignant progression of oral potentially malignant disorders
S Surendran, G Siddappa, A Mohan, W Hicks Jr… - Oral oncology, 2017 - Elsevier
Objective The purpose of this study was to determine association between cancer stem cells
(CSCs) and their niche with progression of oral potentially malignant disorders. Materials …
(CSCs) and their niche with progression of oral potentially malignant disorders. Materials …
Isatin inhibits SH-SY5Y neuroblastoma cell invasion and metastasis through MAO/HIF-1α/CXCR4 signaling
W Sun, L Zhang, L Hou, C Ju, S Zhao, Y Wei - Anti-cancer drugs, 2017 - journals.lww.com
Isatin was reported to possess anticancer activities through its effect on tumor proliferation,
apoptosis, and metastasis in vitro and in vivo. This study aimed to elucidate the underlying …
apoptosis, and metastasis in vitro and in vivo. This study aimed to elucidate the underlying …
Association of cytoplasmic CXCR4 with loss of epithelial marker and activation of ERK1/2 and AKT signaling pathways in non–small-cell Lung Cancer
Objectives Compelling evidence demonstrates that CXC-chemokine receptor 4 (CXCR4) is
involved in tumor invasion, angiogenesis, metastasis, and resistance to chemotherapy in …
involved in tumor invasion, angiogenesis, metastasis, and resistance to chemotherapy in …
Anti-CXCR4 antibodies and antibody-drug conjugates
SH Liu, FM Pernasetti, WH Ho - US Patent 9,708,405, 2017 - Google Patents
WEDDCCIHRLDYTQ-XZZPKJBRSA-N CC [C@ H](C)[C@@ H]([C@@ H](CC (= O) N1CCC
[C@ H] 1 [C@ H](OC)[C@@ H](C) C (= O) C [C@@ H](CC1= CC= CC= C1) C (= O) O) OC) …
[C@ H] 1 [C@ H](OC)[C@@ H](C) C (= O) C [C@@ H](CC1= CC= CC= C1) C (= O) O) OC) …
Phosphorylated CXCR4 expression has a positive prognostic impact in colorectal cancer
B Weixler, F Renetseder, I Facile, N Tosti… - Cellular oncology, 2017 - Springer
Abstract Background The CXCL12-CXCR4 chemokine axis plays an important role in cell
trafficking as well as in tumor progression. In colorectal cancer (CRC), the chemokine …
trafficking as well as in tumor progression. In colorectal cancer (CRC), the chemokine …
High expression of CXC chemokine receptor 4 and Notch1 is predictive of lymphovascular invasion and poor prognosis in lung adenocarcinoma
Z Cong, H Wu, Z Guo, T Qin, Y Xu, H Jing… - Tumor …, 2017 - journals.sagepub.com
CXC chemokine receptor 4 and Notch1 have been shown to play oncogenic role
individually. This study aimed to determine the combinatorial role of CXC chemokine …
individually. This study aimed to determine the combinatorial role of CXC chemokine …
An investigation into the potential role of brain angiogenesis inhibitor protein 3 (BAI3) in the tumorigenesis of small-cell carcinoma: a review of the surrounding …
M Thomas, D Snead, D Mitchell - Journal of Receptors and Signal …, 2017 - Taylor & Francis
Brain angiogenesis inhibitor protein 3 (BAI3) is from the adhesion group of seven-
transmembrane spanning G protein-coupled receptors (GPCRs) and has been identified via …
transmembrane spanning G protein-coupled receptors (GPCRs) and has been identified via …
Expression of CXC motif chemokine receptors 4 and 7 in salivary gland neoplasms
E Phattarataratip, K Dhanuthai - Archives of Oral Biology, 2017 - Elsevier
Objectives Chemokine receptors have been shown to overexpress in several cancer types.
Binding of chemokines to their cognate chemokine receptors on tumor cells can promote …
Binding of chemokines to their cognate chemokine receptors on tumor cells can promote …
Imaging chemokine receptor CXCR4 in chronic infection of the bone with 68Ga-Pentixafor-PET/CT–first insights.
C Bouter, B Meller, CO Sahlmann… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Due to its role in infection and inflammatory processes the chemokine receptor CXCR4
might be a potent target in imaging of infectious and inflammatory diseases. The aim of this …
might be a potent target in imaging of infectious and inflammatory diseases. The aim of this …