Animal models of diabetic retinopathy

AM Olivares, K Althoff, GF Chen, S Wu… - Current diabetes …, 2017 - Springer
Abstract Purpose of Review Diabetic retinopathy (DR) is one of the most common
complications associated with chronic hyperglycemia seen in patients with diabetes mellitus …

Immunogenic and non-immunogenic cell death in the tumor microenvironment

JM Pitt, G Kroemer, L Zitvogel - … in cancer progression and cancer therapy, 2017 - Springer
The host immune system is continuously exposed to dying cells and has evolved to
distinguish between cell death events signaling potential threats and physiological …

Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

S He, PJ Roberts, JA Sorrentino, JE Bisi… - Science translational …, 2017 - science.org
Conventional cytotoxic chemotherapy is highly effective in certain cancers but causes dose-
limiting damage to normal proliferating cells, especially hematopoietic stem and progenitor …

Preoperative controlling nutritional status (CONUT) is useful to estimate the prognosis after esophagectomy for esophageal cancer

N Yoshida, K Harada, Y Baba, K Kosumi… - … archives of surgery, 2017 - Springer
Purpose The aim of this study is to confirm the predictive value of controlling nutritional
status (CONUT), as a postoperative prognostic marker for esophageal cancer patients …

[HTML][HTML] Frailty and inflammatory markers in older adults with cancer

TF Nishijima, AM Deal, GR Williams, EJ Guerard… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
We examined the associations between frailty and inflammatory markers, in particular
neutrophil lymphocyte ratio (NLR), in elderly cancer patients. We conducted cross-sectional …

[HTML][HTML] How many diseases is triple negative breast cancer: the protagonism of the immune microenvironment

DP Saraiva, MG Cabral, A Jacinto, S Braga - Esmo Open, 2017 - Elsevier
Triple negative breast cancer (TNBC) is a type of breast cancer (BC) that does not express
the oestrogen and the progesterone receptors and the human epidermal growth factor …

Radiation-related lymphopenia is associated with spleen irradiation dose during radiotherapy in patients with hepatocellular carcinoma

J Liu, Q Zhao, W Deng, J Lu, X Xu, R Wang, X Li… - Radiation …, 2017 - Springer
Background The decrease in peripheral blood lymphocytes induced by radiation lessens the
antitumour effect of the immune response, which might cause immunosuppression. We …

Evaluation of complete blood count indices (NLR, PLR, MPV/PLT, and PLCRi) in healthy dogs, dogs with periodontitis, and dogs with oropharyngeal tumors as …

A Rejec, J Butinar, J Gawor… - Journal of veterinary …, 2017 - journals.sagepub.com
The aim of the study was to retrospectively assess complete blood count (CBC) indices of
dogs with periodontitis (PD; n= 73) and dogs with oropharyngeal tumors (OT; n= 92) in …

Prognostic significance of preoperative controlling nutritional status (CONUT) score in patients undergoing hepatic resection for hepatocellular carcinoma

N Harimoto, T Yoshizumi, K Sakata, A Nagatsu… - World journal of …, 2017 - Springer
Abstract Background The Controlling Nutritional Status (CONUT) score is an objective tool
widely used to assess nutritional status in patients with inflammatory disease, chronic heart …

The renaissance of anti‐neoplastic immunity from tumor cell demise

Y Ma, JM Pitt, Q Li, H Yang - Immunological reviews, 2017 - Wiley Online Library
Cancer therapies can temporarily reduce tumor burdens by inducing malignant cell death.
However, cancer cure is still far from realization because tumors often gain resistance to …