Sex differences in body composition

MA Bredella - Sex and gender factors affecting metabolic …, 2017 - Springer
Body composition differs between men and women. Men have more lean mass, and women
have more fat mass than men. Men are more likely to accumulate adipose tissue around the …

Mechanisms in endocrinology: skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes: a causal mechanism or an innocent bystander?

C Brøns, LG Grunnet - European Journal of Endocrinology, 2017 - academic.oup.com
Dysfunctional adipose tissue is associated with an increased risk of developing type 2
diabetes (T2D). One characteristic of a dysfunctional adipose tissue is the reduced …

[图书][B] Food lipids: chemistry, nutrition, and biotechnology

CC Akoh - 2017 - taylorfrancis.com
Maintaining the high standards that made the previous editions such well-respected and
widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Fourth Edition …

AMPK regulates lipid accumulation in skeletal muscle cells through FTO-dependent demethylation of N6-methyladenosine

W Wu, J Feng, D Jiang, X Zhou, Q Jiang, M Cai… - Scientific reports, 2017 - nature.com
Skeletal muscle plays important roles in whole-body energy homeostasis. Excessive
skeletal muscle lipid accumulation is associated with some metabolic diseases such as …

Diabetes-induced dysfunction of mitochondria and stem cells in skeletal muscle and the nervous system

S Fujimaki, T Kuwabara - International Journal of Molecular Sciences, 2017 - mdpi.com
Diabetes mellitus is one of the most common metabolic diseases spread all over the world,
which results in hyperglycemia caused by the breakdown of insulin secretion or insulin …

Cellular senescence: Implications for metabolic disease

MJ Schafer, JD Miller, NK LeBrasseur - Molecular and cellular …, 2017 - Elsevier
The growing burden of obesity-and aging-related diseases has hastened the search for
governing biological processes. Cellular senescence is a stress-induced state of stable …

Intramyocellular lipid droplets and insulin sensitivity, the human perspective

A Gemmink, BH Goodpaster, P Schrauwen… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Skeletal muscle can store excess fat as subcellular lipid droplets (LDs). While originally
viewed as uninteresting static balls of triacylglycerol, it is now clear that myocellular LDs play …

Intermuscular adipose tissue and subclinical coronary artery calcification in midlife: the CARDIA study (Coronary Artery Risk Development in Young Adults)

JG Terry, CM Shay, PJ Schreiner… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Excess deposition of fat within and around vital organs and nonadipose tissues
is hypothesized to contribute to cardiovascular disease (CVD) risk. We evaluated the …

Lipid droplet size and location in human skeletal muscle fibers are associated with insulin sensitivity

J Nielsen, AE Christensen… - American Journal …, 2017 - journals.physiology.org
In skeletal muscle, an accumulation of lipid droplets (LDs) in the subsarcolemmal space is
associated with insulin resistance, but the underlying mechanism is not clear. We aimed to …

Effect of 12-month resistance and endurance training on quality, quantity, and function of skeletal muscle in older adults requiring long-term care

A Yoshiko, T Kaji, H Sugiyama, T Koike, Y Oshida… - Experimental …, 2017 - Elsevier
Older adults requiring long-term care will experience age-associated deterioration of the
quality and quantity of skeletal muscle if no interventions are performed. Long-term training …