Oxidative stress in sepsis: pathophysiological implications justifying antioxidant co-therapy

CA Prauchner - Burns, 2017 - Elsevier
Sepsis is one of the main causes of death among critically ill patients. Sepsis pathogenesis
includes infection by gram-negative and gram-positive bacteria, fungi, or both; exacerbated …

Melatonin administration to wild‐type mice and nontreated NLRP 3 mutant mice share similar inhibition of the inflammatory response during sepsis

I Rahim, B Djerdjouri, RK Sayed… - Journal of pineal …, 2017 - Wiley Online Library
The NLRP 3 inflammasome is involved in the innate immune response during inflammation.
Moreover, melatonin blunts the NF‐κB/NLRP 3 connection during sepsis. Thus, we …

N-acetylcysteine-loaded PLGA nanoparticles outperform conventional N-acetylcysteine in acute lung injuries in vivo

AA Karimi Zarchi, MA Faramarzi, K Gilani… - … Journal of Polymeric …, 2017 - Taylor & Francis
Antioxidants potentially play an important role in the control and treatment of acute lung
injury. In this study, for the first time, antioxidant effect of N-acetylcysteine (NAC) was …

[PDF][PDF] Gastric mucosa damage and impairment of secondary immune response in dysthyroidism is associated with TNF-α expression

AF Ajayi, AA Adelakun, RE Akhigbe - Int J Biol Med Res, 2017 - researchgate.net
Aim: This study aims to determine the relationship between immune response in rats with
altered thyroid state and expression of TNF-α in gastric tissue. Methods: Thirty male wistar …

[PDF][PDF] Behavioral, Cognitive, and Biochemical Consequences of Early Life Stress in Later Life: Insights from an Animal Model

H Liu - 2017 - uh-ir.tdl.org
Adverse experiences during early life contribute to the development of psychiatric conditions
in later life. In fact, young children who directly experience or witness traumatic event (s) …

[PDF][PDF] Redox Regulation Mechanisms in Inflammatory Macrophages

M Diotallevi - 2017 - research.brighton.ac.uk
Long-lasting activation of inflammation leads to chronic conditions and is particularly
common in autoimmune diseases. The causes of this self-activation in those conditions are …

[PDF][PDF] A CypD szabályozza a szepszist és a daganatos sejtek életképességét

PJ Krisztián - 2017 - pea.lib.pte.hu
Akt/PKB; protein kinase B; ANT; adenine nucleotide translocase; Bak; BCL2-
antagonist/killer; Bax; BCL2-associated X protein; COX-2; cyclooxygenase-2; CsA; …

N-Acetyl Cysteine Protects Melanoma Specific Cytotoxic T Cells from T Cell Receptor Restimulation Induced Activation of the DNA Damage Response Pathway and …

MJ Scheffel - 2017 - medica-musc.researchcommons.org
The adoptive transfer of autologous melanoma antigen-specific T cells has demonstrated a
remarkable improvement in clinical outcomes for patients with late-stage metastatic …

[引用][C] Kistik fibrozis hastalarında nötrofil fonksiyonları ve sitokin düzeylerinin araştırılması

Ü Aslanhan - platform.almanhal.com
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