In recent years it has been shown that vitamin D deficiency is associated with an increased
incidence as well as the progression of a broad range of diseases including osteoporosis …

The kidneys play a pivotal role in the regulation of electrolyte and acid-base balance. With
progressive loss of kidney function, derangements in electrolytes and acid-base inevitably …

Importance Cohort studies have reported increased incidence of cardiovascular disease
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …

Background Vitamin D deficiency may be a risk factor for mortality but previous meta-
analyses lacked standardization of laboratory methods for 25-hydroxyvitamin D (25 [OH] D) …

There has been substantial enthusiasm recently regarding the potential role of vitamin D in
the primary and secondary prevention of cancer. Laboratory studies demonstrate a range of …

Cardiovascular disease (CVD) prevention is defined as a coordinated set of actions, at the
population level or targeted at an individual, that are aimed at eliminating or minimizing the …

Importance There are long-standing interests in the potential benefits of vitamin D for
preventing breast cancer recurrence and mortality, yet data from prospective cohort studies …

In the last two decades vitamin D (VD) research has demonstrated new extraskeletal actions
of this pre-hormone, suggesting a protective role of this secosteroid in the onset, progression …

Purpose Low vitamin D blood levels are associated with high mortality in critically ill patients.
There is controversy about vitamin D supplementation in this population. The objective of …

Vitamin D has long been established as an elemental factor of bone physiology. Beyond
mineral metabolism, the expression of the vitamin D receptor has been identified throughout …