[HTML][HTML] The future: genetics advances in MEN1 therapeutic approaches and management strategies
SK Agarwal - Endocrine-related cancer, 2017 - ncbi.nlm.nih.gov
The identification of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997 has
shown that germline heterozygous mutations in the MEN1 gene located on chromosome …
shown that germline heterozygous mutations in the MEN1 gene located on chromosome …
[HTML][HTML] Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's old
A Falchetti - F1000Research, 2017 - ncbi.nlm.nih.gov
Despite its identification in 1997, the functions of the MEN1 gene—the main gene underlying
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
[HTML][HTML] Epigenetic regulation by the menin pathway
Z Feng, J Ma, X Hua - Endocrine-related cancer, 2017 - ncbi.nlm.nih.gov
There is a trend of increasing prevalence of neuroendocrine tumors (NETs), and the
inherited multiple endocrine neoplasia type 1 (MEN1) syndrome serves as a genetic model …
inherited multiple endocrine neoplasia type 1 (MEN1) syndrome serves as a genetic model …
Upregulation of RPA2 promotes NF-κB activation in breast cancer by relieving the antagonistic function of menin on NF-κB-regulated transcription
CC Chen, CW Juan, KY Chen, YC Chang… - …, 2017 - academic.oup.com
RPA2, a subunit of the heterotrimeric replication protein A (RPA) complex, is overexpressed
in various cancers. In this study, we showed a significant RPA2 upregulation in breast …
in various cancers. In this study, we showed a significant RPA2 upregulation in breast …
[HTML][HTML] Novel association of MEN1 gene mutations with parathyroid carcinoma
L Cinque, A Sparaneo, F Cetani… - Oncology …, 2017 - spandidos-publications.com
Inactivating mutations of the multiple endocrine neoplasia 1 (MEN1) gene cause MEN1
syndrome, characterized by primary hyperparathyroidism (pHPT), and parathyroid and …
syndrome, characterized by primary hyperparathyroidism (pHPT), and parathyroid and …
Direct interaction of menin leads to ubiquitin-proteasomal degradation of β-catenin
B Kim, TY Song, KY Jung, SG Kim, EJ Cho - Biochemical and biophysical …, 2017 - Elsevier
Menin, encoded by the multiple endocrine neoplasia type 1 (MEN1) gene, is a tumor
suppressor and transcription regulator. Menin interacts with various proteins as a scaffold …
suppressor and transcription regulator. Menin interacts with various proteins as a scaffold …
[PDF][PDF] what's new and what's old [version 1; peer review: 3 approved]
A Falchetti - 2017 - pdfs.semanticscholar.org
Despite its identification in 1997, the functions of the gene—the main MEN1 gene underlying
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
[PDF][PDF] La télomérase: fonctions biologiques et ciblage thérapeutique
P Billard - 2017 - researchgate.net
L'intérêt de la télomérase en recherche n'a jamais été aussi important que depuis la
démonstration de son rôle dans le processus de vieillissement et de cancérogénèse. En …
démonstration de son rôle dans le processus de vieillissement et de cancérogénèse. En …