Evidence-based revised view of the pathophysiology of preeclampsia

A Ahmed, H Rezai, S Broadway-Stringer - Hypertension: from basic …, 2017 - Springer
Preeclampsia is a life-threatening vascular disorder of pregnancy due to a failing stressed
placenta. Millions of women risk death to give birth each year and globally each year, almost …

Aspects of carbon monoxide in form of CO‐releasing molecules used in cancer treatment: more light on the way

M Kourti, WG Jiang, J Cai - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Carbon monoxide (CO) has always been recognised as a toxic gas, due to its higher affinity
for haemoglobin than oxygen. However, biological studies have revealed an intriguing role …

Heme oxygenase (HO)-1 induction prevents endoplasmic reticulum stress-mediated endothelial cell death and impaired angiogenic capacity

H Maamoun, M Zachariah, JH McVey, FR Green… - Biochemical …, 2017 - Elsevier
Most of diabetic cardiovascular complications are attributed to endothelial dysfunction and
impaired angiogenesis. Endoplasmic Reticulum (ER) and oxidative stresses were shown to …

Carbon monoxide prevents TNF-α-induced eNOS downregulation by inhibiting NF-κB-responsive miR-155-5p biogenesis

S Choi, J Kim, JH Kim, DK Lee, W Park… - … & molecular medicine, 2017 - nature.com
Heme oxygenase-1-derived carbon monoxide prevents inflammatory vascular disorders. To
date, there is no clear evidence that HO-1/CO prevents endothelial dysfunction associated …

Carbon Monoxide Potentiation of L-Type Ca2+ Channel Activity Increases HIF-1α-Independent VEGF Expression via an AMPKα/SIRT1-Mediated PGC-1α/ERRα …

YK Choi, JH Kim, DK Lee, KS Lee, MH Won… - Antioxidants & redox …, 2017 - liebertpub.com
Abstract Aims: The heme oxygenase-1 (HO-1)/carbon monoxide (CO) pathway induced in
astrocytes after ischemic brain injury promotes vascular endothelial growth factor (VEGF) …

Ferrochelatase is a therapeutic target for ocular neovascularization

HD Basavarajappa, RS Sulaiman, X Qi… - EMBO molecular …, 2017 - embopress.org
Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related
macular degeneration (AMD). Despite the successes of treatments targeting the vascular …

Circulating total bilirubin and future risk of hypertension in the general population: the Prevention of Renal and Vascular End‐Stage Disease (PREVEND) prospective …

SK Kunutsor, LM Kieneker, S Burgess… - Journal of the …, 2017 - Am Heart Assoc
Background Circulating total bilirubin is known to be inversely and independently
associated with future risk of cardiovascular disease. However, the relationship of circulating …

[PDF][PDF] Молекулярные механизмы действия газотрансмиттеров NO, CO и H2S в гладкомышечных клетках и влияние NO-генерирующих соединений (нитратов …

АВ Носарев, ИВ Петрова… - Успехи физиологических …, 2017 - researchgate.net
Среди сигнальных молекул, участвующих в регуляции внутри-и межклеточных систем в
различных типах клеток, особое место занимают газообразные соединения …

Anticancer activities of manganese-based photoactivatable CO-releasing complexes (PhotoCORMs) with benzimidazole derivative ligands

E Üstün, A Özgür, KA Coşkun… - Transition Metal …, 2017 - Springer
Carbon monoxide is an important signaling molecule which is produced by heme
oxygenase-1. CO shows antiproliferative activity against cancer cells; hence, activation of …

[HTML][HTML] Association of HMGB1 with oxidative stress markers and regulators in PDR

AMA El-Asrar, K Alam, M Garcia-Ramirez… - Molecular …, 2017 - ncbi.nlm.nih.gov
Purpose We investigated the link among the proinflammatory cytokine high-mobility group
box 1 (HMGB1) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a marker of oxidative DNA …