The inhibition of porcine pancreatic α-amylase and mammalian α-glucosidase by 16
individual flavonoids was determined. The IC50 values for baicalein,(+)-catechin, quercetin …

Diabetes mellitus is a metabolic disorder of carbohydrate, lipid and amino-acids
characterized by polyuria, polyphagia, polydypsia, blurred vision etc. It is the most prevailing …

Objective β-Cell dysfunction plays a central role in the pathogenesis of type 2 diabetes
(T2D), and the identification of novel approaches to improve β-cell function is essential to …

The effects of 1, 5-isoquinolinediol (IQD) and nicotinamide (NAm), inhibitors of poly-(ADP-
ribose) polymerase-1 (PARP-1), on inflammatory processes and activation of PARP-1 under …

Objective To evaluate the pathological changes of femoral nerves and the levels of caveolin-
1 in diabetic foot amputation patients with neuropathy, and evaluate the association …

C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero
atoms in the condensed system, at least one ring being a six-membered ring with one …

Актуальность. Среди механизмов, которые приводят к развитию и ухудшению течения
са-харного диабета (СД) 1-го типа и его осложнений, значительная роль принадлежит …

Background. Among the mechanisms that lead to the development and deterioration of the
diabetes mellitus type 1 (DM1) and its complications, an important role belongs to the …

Досліджено вплив інгібіторів поліADPрибозополімерази1 (PARP1)–1, 5 ізохінолін діолу
(ISO) та нікотинаміду (NАm)–на запальні процеси та активацію PARP1 в умовах …