An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

The purpose of this focused update is to update the “2013 ACCF/AHA Guideline for the
Management of Heart Failure” 9 (2013 HF guideline) in areas in which new evidence has …

Aims Pulmonary congestion is an important finding in patients with heart failure (HF) that can
be quantified by lung ultrasound (LUS). We conducted a systematic review to describe …

Background: Despite increased use of guideline-directed medical therapy (GDMT), some
patients with heart failure and reduced ejection fraction (HFrEF) remain at high risk for …

Background: The renin-angiotensin system (RAS) is activated in heart failure (HF) and
inhibition of RAS is a mainstay therapy for HF. Angiotensin-converting enzyme 2 (ACE2) and …

Heart failure is an important cause of morbidity and mortality in women, and they tend to
develop it at an older age compared to men. Heart failure with preserved ejection fraction is …

Background: Elevated pulmonary artery (PA) pressures in patients with heart failure are
associated with a high risk for hospitalization and mortality. Recent clinical trial evidence …

A collective century of discoveries establishes the importance of the renin angiotensin
aldosterone system in maintaining blood pressure, fluid volume and electrolyte homeostasis …

Background—Renin–angiotensin aldosterone system (RAAS) inhibitors significantly
improve outcome in heart failure (HF) patients with reduced ejection fraction (HFREF) …

Background Natriuretic peptides are recognized as important predictors of cardiovascular
events in patients with heart failure, but less is known about their prognostic importance in …