Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy
PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …
Evolution of bacterial virulence
Bacterial virulence is highly dynamic and context-dependent. For this reason, it is
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
challenging to predict how molecular changes affect the growth of a pathogen in a host and …
Host–microbe interactions: Malassezia and human skin
Highlights•Malassezia are dominant eukaryotic microflora of human and animal
skin.•Malassezia interact with the mammalian host in both direct (toxic/irritant) and indirect …
skin.•Malassezia interact with the mammalian host in both direct (toxic/irritant) and indirect …
Immunotherapeutic approaches to treatment of fungal diseases
Fungal infections cause morbidity worldwide and are associated with an unacceptably high
mortality despite the availability of antifungal drugs. The incidence of mycoses is rising …
mortality despite the availability of antifungal drugs. The incidence of mycoses is rising …
[HTML][HTML] Colonizing opportunistic pathogens (COPs): The beasts in all of us
LB Price, BA Hungate, BJ Koch, GS Davis… - PLoS …, 2017 - journals.plos.org
Colonizing opportunistic pathogens (COPs) are microbes that asymptomatically colonize the
human body and, when the conditions are right, can cause infections. Their ability to persist …
human body and, when the conditions are right, can cause infections. Their ability to persist …
[HTML][HTML] Fungal interactions with the human host: exploring the spectrum of symbiosis
Highlights•A model of symbiosis as a function of host damage is proposed.•Transition from
commensalism to parasitism is dependent on host, environmental and fungal …
commensalism to parasitism is dependent on host, environmental and fungal …
CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis
Cryptococcus neoformans is a major fungal pathogen that disseminates to the central
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …
nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune …
[HTML][HTML] Central role of IL-23 and IL-17 producing eosinophils as immunomodulatory effector cells in acute pulmonary aspergillosis and allergic asthma
ES Guerra, CK Lee, CA Specht, B Yadav… - PLoS …, 2017 - journals.plos.org
Aspergillus fumigatus causes invasive pulmonary disease in immunocompromised hosts
and allergic asthma in atopic individuals. We studied the contribution of lung eosinophils to …
and allergic asthma in atopic individuals. We studied the contribution of lung eosinophils to …
[HTML][HTML] Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression
Aspergillus fumigatus is responsible for a disproportionate number of invasive mycosis
cases relative to other common filamentous fungi. While many fungal factors critical for …
cases relative to other common filamentous fungi. While many fungal factors critical for …
Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans
The dynamic response of organisms exposed to environmental pathogens determines their
survival or demise, and the outcome of this interaction depends on the host's susceptibility …
survival or demise, and the outcome of this interaction depends on the host's susceptibility …