Myeloproliferative neoplasms (MPNs) operationally include essential thrombocythemia,
polycythemia vera, primary myelofibrosis (PMF), and prefibrotic PMF. All 4 MPN variants …

Myeloproliferative neoplasms (MPN) are a group of disorders defined by clonal proliferation
of mature myeloid cells with overlapping clinical features. The driver mutations of these …

A decade on from the description of JAK2 V617F, the MPNs are circumscribed by an
increasingly intricate landscape. There is now evidence that they are likely the result of …

Myeloproliferative neoplasms (MPNs), with an expected increment in number, impose
substantial economic and social burdens. To this end, we conducted a nationwide …

Myeloproliferative neoplasm (MPN) is a category in the World Health Organization
classification of myeloid tumors. BCR-ABL1–negative MPN is a subcategory that includes …

Purpose: The PARP inhibitor veliparib delays DNA repair and potentiates cytotoxicity of
multiple classes of chemotherapy drugs, including topoisomerase I inhibitors and platinating …

In this review article, I discuss anemia caused by underlying MDS, a hematologic
malignancy associated with widely varying clinical presentations, mutation patterns, and …

Polycythemia vera is a clonal disorder of hematopoietic stem/progenitor cells. It manifests as
an expansion of red cell mass. It is the most common chronic myeloproliferative neoplasm …

Introduction: Myelofibrosis (MF) is characterized by bone marrow fibrosis with subsequent
extramedullary hematopoiesis and abnormal cytokine expression leading to splenomegaly …

Abstract Purpose of Review The prognosis for patients with Philadelphia chromosome (Ph)-
negative myeloproliferative neoplasms (MPNs) is highly variable. All Ph-negative MPNs …