The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinoma

P Fu, F Chen, Q Pan, X Zhao, C Zhao… - OncoTargets and …, 2017 - Taylor & Francis
Caveolin-1 (Cav-1), a major structural protein of caveolae, is an integral membrane protein
which plays an important role in the progression of carcinoma. However, whether Cav-1 acts …

Caveolae-mediated endocytosis is critical for albumin cellular uptake and response to albumin-bound chemotherapy

M Chatterjee, E Ben-Josef, R Robb, M Vedaie, S Seum… - Cancer research, 2017 - AACR
Nab-paclitaxel, a nanoparticle conjugate of paclitaxel to human albumin, exhibits efficacy in
pancreatic cancer, non–small cell lung cancer and breast cancer. However, there is a lack of …

The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer …

L Mi, F Zhu, X Yang, J Lu, Y Zheng, Q Zhao, X Wen… - Oncogene, 2017 - nature.com
N-myc downstream-regulated gene 1 (NDRG1) has been reported to act as a key regulatory
molecule in tumor progression-related signaling pathways, especially in tumor metastasis …

IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21

AJ Lui, ES Geanes, J Ogony, F Behbod, J Marquess… - Cancer letters, 2017 - Elsevier
Interferon induced transmembrane protein 1 (IFITM1) belongs to a family of interferon
stimulated genes (ISGs) that is associated with tumor progression and DNA damage …

[HTML][HTML] Caveolin-1-mediated STAT3 activation determines electrotaxis of human lung cancer cells

L Li, K Zhang, C Lu, Q Sun, S Zhao, L Jiao, R Han… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Migration of cancer cells leads to the invasion of distant organs by primary tumors. Further,
endogenous electric fields (EFs) in the tumor microenvironment direct the migration of lung …

Correlation of caveolin-1 expression with prognosis in patients with gastric cancer after gastrectomy

M Seker, D Aydin, A Bilici, D Yavuzer… - Oncology research and …, 2017 - karger.com
Summary Background: Upregulation of caveolin-1 (Cav-1) expression is correlated with
histopathological grade and poor prognosis in several human cancers. However, in gastric …

[HTML][HTML] Prognostic significance of epithelial/stromal caveolin‐1 expression in prostatic hyperplasia, high grade prostatic intraepithelial hyperplasia and prostatic …

DA Mohammed, DS Helal - Journal of the Egyptian National Cancer …, 2017 - Elsevier
Caveolin-1 may play a role in cancer development and progression. The aim was to record
the expression and localization of caveolin-1 in benign prostatic hyperplasia (BPH), high …

[HTML][HTML] Anti-neoplastic drugs increase caveolin-1-dependent migration, invasion and metastasis of cancer cells

NI Díaz-Valdivia, CC Calderón, JE Díaz… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Expression of the scaffolding protein Caveolin-1 (CAV1) enhances migration and invasion of
metastatic cancer cells. Yet, CAV1 also functions as a tumor suppressor in early stages of …

Is plasma caveolin-1 level a prognostic biomarker in metastatic pancreatic cancer?

NS Demirci, M Dogan, GU Erdem, S Kacar… - Saudi Journal of …, 2017 - journals.lww.com
Results: The median Cav-1 level was 13.8 ng/mL for the patients with MPC and 12.2 ng/mL
for healthy individuals (P= 0.009). The Cav-1 cut-off level was calculated as 11.6 ng/mL by …

Funktionelle Charakterisierung der Interaktion zwischen dem Multidrug Resistenz 1 Protein und Caveolin-1 und deren Bedeutung für die Radioprotektion von …

J Nehring - 2017 - archiv.ub.uni-heidelberg.de
Bei der Strahlentherapie ist die Bestrahlungsdosis limitiert durch Nebenwirkungen im
Normalgewebe, va in Zellen des hematopoetischen und gastrointestinalen Systems. Eine …