Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
Gut microbiota and IBD: causation or correlation?
J Ni, GD Wu, L Albenberg, VT Tomov - Nature reviews Gastroenterology …, 2017 - nature.com
A general consensus exists that IBD is associated with compositional and metabolic
changes in the intestinal microbiota (dysbiosis). However, a direct causal relationship …
changes in the intestinal microbiota (dysbiosis). However, a direct causal relationship …
Meta-analysis of gut microbiome studies identifies disease-specific and shared responses
Hundreds of clinical studies have demonstrated associations between the human
microbiome and disease, yet fundamental questions remain on how we can generalize this …
microbiome and disease, yet fundamental questions remain on how we can generalize this …
Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models
E Cekanaviciute, BB Yoo, TF Runia… - Proceedings of the …, 2017 - National Acad Sciences
The gut microbiota regulates T cell functions throughout the body. We hypothesized that
intestinal bacteria impact the pathogenesis of multiple sclerosis (MS), an autoimmune …
intestinal bacteria impact the pathogenesis of multiple sclerosis (MS), an autoimmune …
Dysbiosis and the immune system
Throughout the past century, we have seen the emergence of a large number of
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …
Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation
Intestinal colonization by bacteria of oral origin has been correlated with several negative
health outcomes, including inflammatory bowel disease. However, a causal role of oral …
health outcomes, including inflammatory bowel disease. However, a causal role of oral …
The immune response to Prevotella bacteria in chronic inflammatory disease
JM Larsen - Immunology, 2017 - Wiley Online Library
The microbiota plays a central role in human health and disease by shaping immune
development, immune responses and metabolism, and by protecting from invading …
development, immune responses and metabolism, and by protecting from invading …
Gut microbiota dysbiosis contributes to the development of hypertension
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …
Dynamics of the human gut microbiome in inflammatory bowel disease
J Halfvarson, CJ Brislawn, R Lamendella… - Nature …, 2017 - nature.com
Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic
need for increased medication and sometimes even surgery. The aetiology of IBD is partly …
need for increased medication and sometimes even surgery. The aetiology of IBD is partly …
A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients
Background Inflammatory bowel disease (IBD) is characterized by chronic inflammation of
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …