The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

A general consensus exists that IBD is associated with compositional and metabolic
changes in the intestinal microbiota (dysbiosis). However, a direct causal relationship …

Hundreds of clinical studies have demonstrated associations between the human
microbiome and disease, yet fundamental questions remain on how we can generalize this …

The gut microbiota regulates T cell functions throughout the body. We hypothesized that
intestinal bacteria impact the pathogenesis of multiple sclerosis (MS), an autoimmune …

Throughout the past century, we have seen the emergence of a large number of
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …

Intestinal colonization by bacteria of oral origin has been correlated with several negative
health outcomes, including inflammatory bowel disease. However, a causal role of oral …

The microbiota plays a central role in human health and disease by shaping immune
development, immune responses and metabolism, and by protecting from invading …

Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …

Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic
need for increased medication and sometimes even surgery. The aetiology of IBD is partly …

Background Inflammatory bowel disease (IBD) is characterized by chronic inflammation of
the gastrointestinal tract that is associated with changes in the gut microbiome. Here, we …