Five species of parasite cause malaria in humans with the most severe disease caused by
Plasmodium falciparum. Many of the proteins encoded in the P. falciparum genome are …

CD4+ follicular helper T (Tfh) cells have been shown to be critical for the activation of
germinal center (GC) B-cell responses. Similar to other infections, Plasmodium infection …

Naturally acquired immunity against malaria is largely mediated by serum antibodies
controlling levels of blood-stage parasites. A limited understanding of the antigenic targets …

Large-scale molecular epidemiologic studies of Plasmodium falciparum parasites have
provided insights into parasite biology and transmission, can identify the spread of drug …

Background The simian malaria parasite Plasmodium knowlesi has been reported to cause
significant numbers of human infection in South East Asia. Its merozoite surface protein-3 …

Background Plasmodium falciparum reticulocyte-binding protein homologue 2b (PfRh2b) is
an invasion ligand that is a potential blood-stage vaccine candidate antigen; however, a …

Background Plasmodium falciparum SURFIN 4.1 is a putative ligand expressed on the
merozoite and likely on the infected red blood cell, whose gene was suggested to be under …

Malaria affects almost half of the worlds population causing more than 200 million clinical
cases each year and thus, remains one of the major infectious diseases of mankind. The …

We examined malaria infection in asymptomatic blood donors from Mali, analyzing allelic
diversity of Plasmodium falciparum (Pf) merozoite surface proteins (msp)-1 and-2 as well as …

Dengue viruses (DENV) and other mosquito-borne flaviviruses are rapidly emerging human
pathogens that threaten nearly half of the world's population. There is currently no effective …