[HTML][HTML] Karyotype stability and unbiased fractionation in the paleo-allotetraploid Cucurbita genomes
The Cucurbita genus contains several economically important species in the Cucurbitaceae
family. Here, we report high-quality genome sequences of C. maxima and C. moschata and …
family. Here, we report high-quality genome sequences of C. maxima and C. moschata and …
Genome annotation for clinical genomic diagnostics: strengths and weaknesses
CA Steward, APJ Parker, BA Minassian, SM Sisodiya… - Genome medicine, 2017 - Springer
Abstract The Human Genome Project and advances in DNA sequencing technologies have
revolutionized the identification of genetic disorders through the use of clinical exome …
revolutionized the identification of genetic disorders through the use of clinical exome …
The bottle gourd genome provides insights into Cucurbitaceae evolution and facilitates mapping of a Papaya ring‐spot virus resistance locus
Bottle gourd (Lagenaria siceraria) is an important vegetable crop as well as a rootstock for
other cucurbit crops. In this study, we report a high‐quality 313.4‐Mb genome sequence of a …
other cucurbit crops. In this study, we report a high‐quality 313.4‐Mb genome sequence of a …
[HTML][HTML] Data management and data enrichment for systems biology projects
U Wittig, M Rey, A Weidemann, W Müller - Journal of biotechnology, 2017 - Elsevier
Collecting, curating, interlinking, and sharing high quality data are central to de. NBI-SysBio,
the systems biology data management service center within the de. NBI network (German …
the systems biology data management service center within the de. NBI network (German …
Integrating next-generation genomic sequencing and mass spectrometry to estimate allele-specific protein abundance in human brain
Gene expression contributes to phenotypic traits and human disease. To date,
comparatively less is known about regulators of protein abundance, which is also under …
comparatively less is known about regulators of protein abundance, which is also under …
Influence of V54M mutation in giant muscle protein titin: a computational screening and molecular dynamics approach
D Thirumal Kumar, C George Priya Doss… - Journal of …, 2017 - Taylor & Francis
Recent genetic studies have revealed the impact of mutations in associated genes for
cardiac sarcomere components leading to dilated cardiomyopathy (DCM). The cardiac …
cardiac sarcomere components leading to dilated cardiomyopathy (DCM). The cardiac …
Bioinformatics meets biomedicine: OncoFinder, a quantitative approach for interrogating molecular pathways using gene expression data
AA Buzdin, V Prassolov, AA Zhavoronkov… - Biological Networks and …, 2017 - Springer
We propose a biomathematical approach termed OncoFinder (OF) that enables performing
both quantitative and qualitative analyses of the intracellular molecular pathway activation …
both quantitative and qualitative analyses of the intracellular molecular pathway activation …
Design of novel lead molecules against RhoG protein as cancer target–a computational study
T Dasari, B Kondagari, R Dulapalli… - Journal of …, 2017 - Taylor & Francis
Cancer is a class of diseases characterized by uncontrolled cell growth. Every year more
than 2 million people are affected by the disease. Rho family proteins are actively involved …
than 2 million people are affected by the disease. Rho family proteins are actively involved …
Whole genome sequencing of Guzerá cattle reveals genetic variants in candidate genes for production, disease resistance, and heat tolerance
In bovines, artificial selection has produced a large number of breeds which differ in
production, environmental adaptation, and health characteristics. To investigate the genetic …
production, environmental adaptation, and health characteristics. To investigate the genetic …
Integrated analysis of zone-specific protein and metabolite profiles within nitrogen-fixing Medicago truncatula-Sinorhizobium medicae nodules
Symbiotic nitrogen fixation (SNF) between rhizobia and legumes requires metabolic
coordination within specialized root organs called nodules. Nodules formed in the symbiosis …
coordination within specialized root organs called nodules. Nodules formed in the symbiosis …