Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's …

MA Daulatzai - Journal of neuroscience research, 2017 - Wiley Online Library
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

[HTML][HTML] The gut-brain axis in Parkinson's disease: possibilities for food-based therapies

P Perez-Pardo, T Kliest, HB Dodiya… - European journal of …, 2017 - Elsevier
Parkinson's disease (PD) is usually characterized by cardinal motor impairments. However,
a range of non-motor symptoms precede the motor-phase and are major determinants for …

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

H Soininen, A Solomon, PJ Visser, SB Hendrix… - The Lancet …, 2017 - thelancet.com
Background Nutrition is an important modifiable risk factor in Alzheimer's disease. Previous
trials of the multinutrient Fortasyn Connect showed benefits in mild Alzheimer's disease …

[HTML][HTML] Nutrition for the ageing brain: towards evidence for an optimal diet

D Vauzour, M Camprubi-Robles… - Ageing research …, 2017 - Elsevier
As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders …

Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention: Thematic Review Series: ApoE and Lipid …

MOW Grimm, DM Michaelson, T Hartmann - Journal of lipid research, 2017 - ASBMB
In the last decade, it has become obvious that Alzheimer's disease (AD) is closely linked to
changes in lipids or lipid metabolism. One of the main pathological hallmarks of AD is …

[HTML][HTML] A specific dietary intervention to restore brain structure and function after ischemic stroke

M Wiesmann, B Zinnhardt, D Reinhardt… - Theranostics, 2017 - ncbi.nlm.nih.gov
Occlusion of the middle cerebral artery (MCAo) is among the most common causes of
ischemic stroke in humans. Cerebral ischemia leads to brain lesions existing of an …

[HTML][HTML] Hypertension, cerebrovascular impairment, and cognitive decline in aged AβPP/PS1 mice

M Wiesmann, V Zerbi, D Jansen, D Lütjohann… - Theranostics, 2017 - ncbi.nlm.nih.gov
Cardiovascular risk factors, especially hypertension, are also major risk factors for
Alzheimer's disease (AD). To elucidate the underlying vascular origin of neurodegenerative …

Promising effects of neurorestorative diets on motor, cognitive, and gastrointestinal dysfunction after symptom development in a mouse model of Parkinson's disease

P Perez-Pardo, EM De Jong, LM Broersen… - Frontiers in Aging …, 2017 - frontiersin.org
Parkinson's disease (PD) is characterized by the progressive degeneration of dopaminergic
nigrostriatal neurons, with reductions in the function and amount of dopaminergic synapses …

Angiotensin II, hypertension and angiotensin II receptor antagonism: Roles in the behavioural and brain pathology of a mouse model of Alzheimer's disease

M Wiesmann, M Roelofs… - Journal of Cerebral …, 2017 - journals.sagepub.com
Elevated angiotensin II causes hypertension and contributes to Alzheimer's disease by
affecting cerebral blood flow. Angiotensin II receptor blockers may provide candidates to …

Quantitative erythrocyte omega-3 EPA plus DHA levels are related to higher regional cerebral blood flow on brain SPECT

DG Amen, WS Harris, PM Kidd… - Journal of …, 2017 - content.iospress.com
Background: The interrelationships between omega-3 fatty acids status, brain perfusion, and
cognition are not well understood. Objective: To evaluate if SPECT brain imaging of cerebral …