Edited 1H magnetic resonance spectroscopy in vivo: Methods and metabolites

AD Harris, MG Saleh… - Magnetic resonance in …, 2017 - Wiley Online Library
The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …

Big GABA: Edited MR spectroscopy at 24 research sites

M Mikkelsen, PB Barker, PK Bhattacharyya, MK Brix… - Neuroimage, 2017 - Elsevier
Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …

Occipital GABA levels in older adults and their relationship to visual perceptual suppression

K Pitchaimuthu, Q Wu, O Carter, BN Nguyen, S Ahn… - Scientific Reports, 2017 - nature.com
Several studies have attributed certain visual perceptual alterations in older adults to a likely
decrease in GABA (Gamma Aminobutyric Acid) concentration in visual cortex, an …

Activation induced changes in GABA: functional MRS at 7 T with MEGA-sLASER

C Chen, HP Sigurdsson, SE Pépés, DP Auer… - Neuroimage, 2017 - Elsevier
Functional magnetic resonance spectroscopy (fMRS) has been used to assess the dynamic
metabolic responses of the brain to a physiological stimulus non-invasively. However, only …

Simultaneous measurement of Aspartate, NAA, and NAAG using HERMES spectral editing at 3 Tesla

KL Chan, MG Saleh, G Oeltzschner, PB Barker… - Neuroimage, 2017 - Elsevier
It has previously been shown that the HERMES method ('Hadamard Encoding and
Reconstruction of MEGA-Edited Spectroscopy') can be used to simultaneously edit pairs of …

Dual‐volume excitation and parallel reconstruction for J‐difference‐edited MR spectroscopy

G Oeltzschner, NAJ Puts, KL Chan… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To develop J‐difference editing with parallel reconstruction in accelerated
multivoxel (PRIAM) for simultaneous measurement in two separate brain regions of γ …

Real-time frequency and motion corrected Hadamard encoded spectral editing (CHASE)

A Marsman, VO Boer, M Andersen… - Proc Intl Soc Mag …, 2017 - archive.ismrm.org
Inhibitory neurotransmitter GABA and antioxidant GSH are suggested to be implicated in
psychiatric and neurological disorders. These metabolites can be measured in the human …

MEGA-PRIAM: Dual-volume excitation and parallel reconstruction for J-difference-edited MR spectroscopy

G Oeltzschner, NA Puts, KL Chan… - Proceedings of the …, 2017 - archive.ismrm.org
A twofold acceleration of MEGA-edited spectroscopy, using Parallel Reconstruction In
Accelerated Multivoxel (MEGA-PRIAM) to simultaneously acquire data in two separate …

Human brain imaging in HIV and neuroAIDS

MA Mohamed - Global Virology II-HIV and NeuroAIDS, 2017 - Springer
The introduction of combination antiretroviral therapy (cART) has significantly decreased the
severity of HIV-associated neurocognitive disorder (HAND) and increased the life …

Research Progress of Gamma-Aminobutyric Acid (GABA)

C Tan, X Yan, X Wu, C Zhu, M Gou… - 2017 6th International …, 2017 - atlantis-press.com
Authores reviewed GABA's physiological functions, preparation methods and the
development prospects. Earlier researchers produced GABA by chemical synthesis method …