Positioning metal-organic framework nanoparticles within the context of drug delivery–a comparison with mesoporous silica nanoparticles and dendrimers

S Wuttke, M Lismont, A Escudero, B Rungtaweevoranit… - Biomaterials, 2017 - Elsevier
Nanotechnology enables the creation of delivery vehicles able to overcome physiologically
imposed barriers, allowing new approaches for reducing the unwanted side effects of …

Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery

H Li, N Lv, X Li, B Liu, J Feng, X Ren, T Guo, D Chen… - Nanoscale, 2017 - pubs.rsc.org
Metal–organic frameworks (MOFs), which are typically embedded in polymer matrices as
composites, are emerging as a new class of carriers for sustained drug delivery. Most of the …

New insights into the degradation mechanism of metal-organic frameworks drug carriers

X Li, L Lachmanski, S Safi, S Sene, C Serre… - Scientific reports, 2017 - nature.com
A versatile method based on Raman microscopy was developed to follow the degradation of
iron carboxylate Metal Organic Framework (MOF) nano-or micro-particles in simulated body …

A smart metal–organic framework nanomaterial for lung targeting

T Simon‐Yarza, M Giménez‐Marqués… - Angewandte …, 2017 - Wiley Online Library
Despite high morbidity and mortality associated with lung diseases, addressing drugs
towards lung tissue remains a pending task. Particle lung filtration has been proposed for …

A non-covalent “click chemistry” strategy to efficiently coat highly porous MOF nanoparticles with a stable polymeric shell

A Aykaç, M Noiray, M Malanga, V Agostoni… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Metal-organic framework nanoparticles (nanoMOFs) are biodegradable highly
porous materials with a remarkable ability to load therapeutic agents with a wide range of …

Towards improved HIV-microbicide activity through the co-encapsulation of NRTI drugs in biocompatible metal organic framework nanocarriers

MT Marcos-Almaraz, R Gref, V Agostoni… - Journal of Materials …, 2017 - pubs.rsc.org
The efficacy of the routinely used anti-HIV (Human Immunodeficiency Virus) therapy based
on nucleoside reverse transcriptase inhibitors (NRTIs) is limited by the poor cellular uptake …

[PDF][PDF] 4.38 The situation of Metal-Organic Frameworks in Biomedicine

T Simon-Yarza, S Rojas, P Horcajada… - Compr. Biomater. II; …, 2017 - researchgate.net
BIX 1, 4-bis (imidazol-1-ylmethyl) benzene BPDC 2, 20-bipyridine-6, 60-dicarboxylate BPDC
4, 40-biphenyldicarboxylic acid. BPY 2, 20-bipyridine Br-BODIPY 1, 3, 5, 7-tetramethyl-4, 4 …

" Cage" Nano and Micro-particles for Biomedical Applications

X Li - 2017 - theses.hal.science
Drug delivery systems are engineered technologies to administer pharmaceutical
ingredients to improve their therapeutic effects, aiming at minimizing their side effects by …