Crosstalk between stromal cells and cancer cells in pancreatic cancer: New insights into stromal biology
H Zhan, B Zhou, Y Cheng, J Xu, L Wang, G Zhang… - Cancer letters, 2017 - Elsevier
Pancreatic cancer (PC) remains one of the most lethal malignancies worldwide. Increasing
evidence has confirmed the pivotal role of stromal components in the regulation of …
evidence has confirmed the pivotal role of stromal components in the regulation of …
Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut
P Chairatana, EM Nolan - Critical reviews in biochemistry and …, 2017 - Taylor & Francis
In the intestine, the mucosal immune system plays essential roles in maintaining
homeostasis between the host and microorganisms, and protecting the host from pathogenic …
homeostasis between the host and microorganisms, and protecting the host from pathogenic …
Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Delivery and formulation of engineered nucleic acids
A De Fougerolles, SM Elbashir - US Patent 9,533,047, 2017 - Google Patents
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A combination of MUC5AC and CA19-9 improves the diagnosis of pancreatic cancer: a multicenter study
OBJECTIVES: Pancreatic cancer (PC) is a lethal malignancy that lacks specific diagnostic
markers. The present study explores the diagnostic potential of the most differentially …
markers. The present study explores the diagnostic potential of the most differentially …
[HTML][HTML] Never let it go: Stopping key mechanisms underlying metastasis to fight pancreatic cancer
E Giovannetti, CL Van Der Borden, AE Frampton… - Seminars in cancer …, 2017 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive neoplasm, predicted
to become the second leading cause of cancer-related deaths before 2030. This dismal …
to become the second leading cause of cancer-related deaths before 2030. This dismal …
Engineered nucleic acids and methods of use thereof
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Gene signature driving invasive mucinous adenocarcinoma of the lung
M Guo, K Tomoshige, M Meister, T Muley… - EMBO molecular …, 2017 - embopress.org
Though invasive mucinous adenocarcinoma of the lung (IMA) is pathologically distinctive,
the molecular mechanism driving IMA is not well understood, which hampers efforts to …
the molecular mechanism driving IMA is not well understood, which hampers efforts to …
Modified polynucleotides encoding hepatitis A virus cellular receptor 2
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2017 - Google Patents
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MUC4 mucin-a therapeutic target for pancreatic ductal adenocarcinoma
Introduction: Pancreatic cancer (PC) is characterized by mucin overexpression. MUC4 is the
most differentially overexpressed membrane-bound mucin that plays a functional role in …
most differentially overexpressed membrane-bound mucin that plays a functional role in …