Oxidative stress, protein modification and Alzheimer disease
A Tramutola, C Lanzillotta, M Perluigi… - Brain research bulletin, 2017 - Elsevier
Alzheimer disease (AD) is a progressive neurodegenerative disease that affects the elderly
population with complex etiology. Many hypotheses have been proposed to explain different …
population with complex etiology. Many hypotheses have been proposed to explain different …
[HTML][HTML] Neurodegeneration in diabetic retinopathy: potential for novel therapies
AJ Barber, B Baccouche - Vision research, 2017 - Elsevier
The complex pathology of diabetic retinopathy (DR) affects both vascular and neural tissue.
The characteristics of neurodegeneration are well-described in animal models but have …
The characteristics of neurodegeneration are well-described in animal models but have …
Alpha-lipoic acid attenuates acute neuroinflammation and long-term cognitive impairment after polymicrobial sepsis
Sepsis is a complication of an infection which imbalance the normal regulation of several
organ systems, including the central nervous system (CNS). Evidence points towards …
organ systems, including the central nervous system (CNS). Evidence points towards …
L-F001, a novel multifunctional ROCK inhibitor, suppresses neuroinflammation in vitro and in vivo: Involvement of NF-κB inhibition and Nrf2 pathway activation
J Chen, W Yin, Y Tu, S Wang, X Yang, Q Chen… - European journal of …, 2017 - Elsevier
Microglia and astrocytes are largely responsible for inflammatory injury in the brain of
Alzheimer's disease (AD). Increasing evidence has indicated that Rho kinase (ROCK) plays …
Alzheimer's disease (AD). Increasing evidence has indicated that Rho kinase (ROCK) plays …
The potential protective effect of α-lipoic acid against nanocopper particle–induced hepatotoxicity in male rats
The present research task is aimed to evaluate the role of exogenous α-lipoic acid
(ALA)(100 mg/kg body weight) as hepatoprotective and potent antioxidant in amelioration of …
(ALA)(100 mg/kg body weight) as hepatoprotective and potent antioxidant in amelioration of …
Bioresponsive Chimaeric Nanopolymersomes Enable Targeted and Efficacious Protein Therapy for Human Lung Cancers in Vivo
Rapidly evolving protein technology has generated hundreds of therapeutic proteins that are
promising for treating various human diseases. The clinical use of protein drugs remains …
promising for treating various human diseases. The clinical use of protein drugs remains …
Efficient delivery of paclitaxel into ASGPR over-expressed cancer cells using reversibly stabilized multifunctional pullulan nanoparticles
L Huang, Y Wang, X Ling, B Chaurasiya, C Yang… - Carbohydrate …, 2017 - Elsevier
Core-crosslinked pullulan nanoparticles (Pull-LA-CLNPs) were synthesized by the reduction-
sensitive strategy for paclitaxel (PTX) delivery. Pull-LA-CLNPs showed high stability against …
sensitive strategy for paclitaxel (PTX) delivery. Pull-LA-CLNPs showed high stability against …
Polymeric drug delivery micelle-like nanocarriers for pulmonary administration of beclomethasone dipropionate
D Triolo, EF Craparo, B Porsio, C Fiorica… - Colloids and Surfaces B …, 2017 - Elsevier
In this paper, the potential of novel polymeric micelles as drug delivery systems for
Beclomethasone Dipropionate (BDP) administration into the lung is investigated. These …
Beclomethasone Dipropionate (BDP) administration into the lung is investigated. These …
Lipoic acid functionalized SiO2@ Ag nanoparticles. Synthesis, characterization and evaluation of biological activity
A novel nanocomposite was obtained through the covalent immobilization of lipoic acid on
the surface of silver nanoparticles-decorated silica nanoparticles (SiO 2@ Ag). The hybrid …
the surface of silver nanoparticles-decorated silica nanoparticles (SiO 2@ Ag). The hybrid …
[HTML][HTML] A novel DSC approach for evaluating protectant drugs efficacy against dementia
Differential scanning calorimetry was applied to evaluate the efficacy of preventive
treatments with biologically active compounds of plant origin against neurodegenerative …
treatments with biologically active compounds of plant origin against neurodegenerative …