Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …

The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen
causing acute and chronic infections in predisposed human subjects. Here we review recent …

Emergence of epidemic clones and antibiotic resistance development compromises the
management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections …

To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-
cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the …

While much attention has been focused on acquired antibiotic resistance genes,
chromosomal mutations may be most important in chronic infections where isolated …

The loss of effective antimicrobials is reducing our ability to protect the global population
from infectious disease. However, the field of antibiotic drug discovery and the public health …

Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …

Over the past decade, there has been a rising interest in Achromobacter sp., an emerging
opportunistic pathogen responsible for nosocomial and cystic fibrosis lung infections …

Genetic determinants of antibiotic resistance (AR) have been extensively investigated. High-
throughput sequencing allows for the assessment of the relationship between genotype and …

Introduction: Antimicrobial susceptibility testing is key in modern clinical microbiology. With
pandemic emergence of (multi-) antibiotic resistance, methods to detect and quantify …