[HTML][HTML] TRPP2 ion channels: critical regulators of organ morphogenesis in health and disease

T Busch, M Köttgen, A Hofherr - Cell Calcium, 2017 - Elsevier
Ion channels control the membrane potential and mediate transport of ions across
membranes. Archetypical physiological functions of ion channels include processes such as …

Posttranslational modifications of neuroligins regulate neuronal and glial signaling

J Jeong, JD Paskus, KW Roche - Current Opinion in Neurobiology, 2017 - Elsevier
Highlights•NLGNs are regulated by multiple posttranslational modifications.•
Posttranslational modifications allow isoform-specific NLGN functions.•Activity-dependent …

Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro

A Oberhofer, P Spieler, Y Rosenfeld… - Proceedings of the …, 2017 - National Acad Sciences
Pigment organelles, or melanosomes, are transported by kinesin, dynein, and myosin
motors. As such, melanosome transport is an excellent model system to study the functional …

Phosphoproteomic analysis of paper mulberry reveals phosphorylation functions in chilling tolerance

Z Pi, ML Zhao, XJ Peng, SH Shen - Journal of Proteome …, 2017 - ACS Publications
Paper mulberry is a valuable woody species with a good chilling tolerance. In this study,
phosphoproteomic analysis, physiological measurement, and mRNA quantification were …

Structural mechanism underlying regulation of human EFhd2/Swiprosin-1 actin-bundling activity by Ser183 phosphorylation

KR Park, JY An, JY Kang, JG Lee, Y Lee… - Biochemical and …, 2017 - Elsevier
EF-hand domain-containing protein D2/Swiprosin-1 (EFhd2) is an actin-binding protein
mainly expressed in the central nervous and the immune systems of mammals. Intracellular …

Systematic synergy of glucose and GLP-1 to stimulate insulin secretion revealed by quantitative Phosphoproteomics

J Tang, Q Li, J Li, J Wu, R Zeng - Scientific Reports, 2017 - nature.com
GLP-1 synergizes with glucose in regulating pancreatic β-cell function, including facilitating
β-cell survival and insulin secretion. Though it has been widely accepted that …

Identification of kinases phosphorylating 13 sites in the nuclear, DNA-binding protein NUCKS

K Grundt, B Thiede, AC Østvold - … et Biophysica Acta (BBA)-Proteins and …, 2017 - Elsevier
NUCKS is a vertebrate specific, nuclear and DNA-binding phospho protein. The protein is
highly expressed in rapidly dividing cells, and is overexpressed in a number of cancer …

[HTML][HTML] Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry

M del Mar Masdeu, BG Armendáriz, A La Torre… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Ack1 (activated Cdc42-associated tyrosine kinase) is a non-receptor tyrosine
kinase that is highly expressed in brain. This kinase contains several protein-protein …

Mechanistic dissection of myosin Va-based melanosome transport in vitro

A Oberhofer - 2017 - edoc.ub.uni-muenchen.de
Essenzielle zelluläre Prozesse wie Zellwachstum, Teilung und Transport von Cargo sind auf
intrazellulären Transport angewiesen. Die dafür verantwortliche Transportmaschinerie …

[PDF][PDF] Die Phosphorylierung von Plakophilin3 durch die p70-S6-Kinase und ihr Einfluss auf Funktion und Lokalisation

MC Möllmer - 2017 - opendata.uni-halle.de
1996; Sirotkin et al., 1997; Paffenholz und Franke, 1997) und die Plakophilin-Subfamilie mit
Plakophilin1 bis 3 (PKP1-3, Hatzfeld et al., 1994; Mertens et al., 1996; Bonné et al., 1999; …