Studies of induced pluripotent stem cells (iPSCs) from schizophrenia patients and control
individuals revealed that the disorder is programmed at the preneuronal stage, involves a …

The watershed-hypothesis of schizophrenia asserts that over 200 different mutations
dysregulate distinct pathways that converge on an unspecified common mechanism (s) that …

Background Amotivation is prevalent in first-episode psychosis (FEP) patients and is a major
determinant of functional outcome. Prediction of amotivation in the early stage of psychosis …

Rationale Motivated behavior can be characterized by a substantial exertion of effort, and
organisms often make effort-related decisions based upon analyses of work-related …

Working holds an important role in society and is the considered normal thing to do. While
the majority of people with schizophrenia would like to work, employment rates remain …

Motivation deficits are a prevalent and pervasive symptom in schizophrenia, and are
inextricably linked to poor functional outcomes in affected individuals. The primary objective …

Schizophrenia is one of the most serious mental illnesses that affects over 21 million people
worldwide (WHO, 2016). A study was carried out in order to find new computer-assisted …

[spa] Multitud de estudios diferentes han dedicado gran cantidad de esfuerzo al estudio de
la motivación en pacientes con trastornos mentales. La esquizofrenia es uno de los …

Motivational deficits have long been viewed as a core feature of schizophrenia. In recent
years, there has been an increased focus on the role of motivation in cognitive remediation …