Mass spectrometry for the discovery of biomarkers of sepsis

KR Ludwig, AB Hummon - Molecular BioSystems, 2017 - pubs.rsc.org
Sepsis is a serious medical condition that occurs in 30% of patients in intensive care units
(ICUs). Early detection of sepsis is key to prevent its progression to severe sepsis and septic …

[HTML][HTML] Treatment of sepsis: What is the antibiotic choice in bacteremia due to carbapenem resistant Enterobacteriaceae?

F Alhashem, NL Tiren-Verbeet, E Alp… - World journal of clinical …, 2017 - ncbi.nlm.nih.gov
Sepsis is one of the major challenges of today. Although gram-positive bacteria related
infections are more prevalent in hospital setting, the highest mortality rate is associated with …

Racial disparities in sepsis-related in-hospital mortality: using a broad case capture method and multivariate controls for clinical and hospital variables, 2004–2013

JM Jones, KR Fingar, MA Miller, R Coffey… - Critical Care …, 2017 - journals.lww.com
Objectives: As sepsis hospitalizations have increased, in-hospital sepsis deaths have
declined. However, reported rates may remain higher among racial/ethnic minorities. Most …

A national study of the effect of race, socioeconomic status, and gender on burn outcomes

H Bedri, KS Romanowski, J Liao… - Journal of Burn Care …, 2017 - academic.oup.com
Age, burn size, and inhalation injury are the major contributing variables related to burn
mortality. While the female gender has been linked to higher mortality, the impact of …

[HTML][HTML] Septic shock

S Mahapatra, AC Heffner - 2017 - europepmc.org
Objectives: Review the causes of septic shock. Describe the pathophysiology of septic
shock. Outline the treatment options for septic shock. Explain the importance of improving …

Thioredoxin-1 attenuates sepsis-induced cardiomyopathy after cecal ligation and puncture in mice

RL Wilson, V Selvaraju, R Lakshmanan… - Journal of Surgical …, 2017 - Elsevier
Background Sepsis is a leading cause of mortality among patients in intensive care units
across the USA. Thioredoxin-1 (Trx-1) is an essential 12 kDa cytosolic protein that, apart …

Sepsis and septic shock

Y Mehta, G Kochhar - Journal of Cardiac Critical Care TSS, 2017 - thieme-connect.com
The term “sepsis” is derived from Greek word “sepo” meaning “I rot” and was first introduced
in the poems of Homer (ca. 18th century BC). Sepsis and septic shock are among the major …

High mortality due to sepsis in Native Hawaiians and African Americans: the multiethnic cohort

ML Matter, YB Shvetsov, C Dugay, CA Haiman… - PLoS …, 2017 - journals.plos.org
Background/Objectives Sepsis is a severe systemic response to infection with a high
mortality rate. A higher incidence has been reported for older people, in persons with a …

Analysis of race and time to antibiotics among patients with severe sepsis or septic shock

TE Madsen, AM Napoli - Journal of Racial and Ethnic Health Disparities, 2017 - Springer
Abstract Background/Objectives The objective of this study is to investigate potential racial
disparities in time to antibiotics among patients presenting to the emergency department …

[PDF][PDF] Biomarkers of necrotising soft tissue infections

MB Hansen - Dan Med J, 2017 - content.ugeskriftet.dk
Necrotising soft tissue infection (NSTI) was first described by Hippocrates in the 5th century
BC as a complication of erysipelas:“many were attacked by the erysipelas all over the body …