Methods to induce targeted protein degradation through bifunctional molecules

J Bradner, D Buckley, G Winter - US Patent 9,821,068, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
56128661&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods to induce targeted protein degradation through bifunctional molecules

J Bradner, D Buckley, G Winter - US Patent 9,750,816, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
56128661&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Spirocyclic degronimers for target protein degradation

AJ Phillips, CG Nasveschuk, JA Henderson, Y Liang… - 2017 - Google Patents
WO2017197036A1 - Spirocyclic degronimers for target protein degradation - Google Patents
WO2017197036A1 - Spirocyclic degronimers for target protein degradation - Google Patents …

C3-Carbon linked glutarimide degronimers for target protein degradation

AJ Phillips, CG NASVESCHUK, JA Henderson, Y Liang… - 2017 - Google Patents
UEJJHQNACJXSKW-UHFFFAOYSA-N 2-(2, 6-dioxopiperidin-3-yl)-1H-isoindole-1, 3 (2H)-
dione Chemical compound O= C1C2= CC= CC= C2C (= O) N1C1CCC (= O) NC1= O …

Ash1l inhibitors and methods of treatment therewith

J Grembecka, T Cierpicki, D ROGAWSKI, D Borkin… - 2017 - Google Patents
WO2017197240A1 - Ash1l inhibitors and methods of treatment therewith - Google Patents
WO2017197240A1 - Ash1l inhibitors and methods of treatment therewith - Google Patents …