Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

Autophagy contributes to the maintenance of intracellular homeostasis in most cells of
cardiovascular origin, including cardiomyocytes, endothelial cells, and arterial smooth …

Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension.
Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial remodelling in …

Diabetic cardiomyopathy (DCM) is often associated with suppressed cardiac autophagy,
mitochondrial structural and functional impairment. Sirtuin-3 (Sirt3) has been reported to …

Autophagy is a ubiquitous cellular catabolic process responsive to energy stress. Research
over the past decade has revealed that cardiomyocyte autophagy is a prominent …

Despite advances in myocardial reperfusion therapies, acute myocardial
ischaemia/reperfusion injury and consequent ischaemic heart failure represent the number …

A plethora of environmental and behavioral factors interact, resulting in changes in gene
expression and providing a basis for the development and progression of cardiovascular …

Pretreatment of berbamine protects the heart from ischemia/reperfusion (I/R) injury. However
it is unknown whether it has cardioprotection when given at the onset of reperfusion …

Podocytes are highly differentiated epithelial cells wrapping glomerular capillaries to form
the filtration barrier in kidneys. As such, podocyte injury or dysfunction is a critical …

Autophagy is a lysosomal degradation pathway of eukaryotic cells that is highly conserved
from yeast to mammals. During this process, cooperating protein complexes are recruited in …