The interactions of chemokines with their G protein-coupled receptors promote the migration
of leukocytes during normal immune function and as a key aspect of the inflammatory …

Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

Chemokines orchestrate cell migration for development, immune surveillance, and disease
by binding to cell surface heterotrimeric guanine nucleotide–binding protein (G protein) …

Viruses use diverse strategies to elude the immune system, including copying and
repurposing host cytokine and cytokine receptor genes. For herpesviruses, the chemokine …

Emerging evidence demonstrates that the stromal derived factor-1 (SDF-1α)/CXCR4 axis is
associated with tumor aggressiveness and metastasis, including glioma, the most common …

Certain viruses have the ability to subvert the mammalian immune response, including
interference in the chemokine system. Poxviruses produce the chemokine binding protein …

BACKGROUND Serum‐prostate specific antigen (PSA) levels have been used for many
years as a biomarker for prostate cancer. This usage is under scrutiny due to the fact that …

The human immune system is among one of the most complex organ systems in the human
body. While it is responsible for healing wounds and protecting from disease, it can also …

ABSTRACT A novel cytokine, U83A, is described, as are variant forms of the cytokine,
having a wide range of agonistic and antagonistic activity against chemokine receptors …

Breast cancer (BrCa) metastasis is a process mediated by the expression of chemokine
receptors by BrCa cells, which migrate towards their chemokine ligands presented by …