Hypertension, a global public health problem, is currently the leading factor in the global
burden of disease. It is the major modifiable risk factor for heart disease, stroke and kidney …

Background Sodium‐glucose cotransporter 2 (SGLT2) inhibitors are a novel class of
antihyperglycemic agents that improve glycemic control by increasing glycosuria. Additional …

Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Parents of children with Autism Spectrum Disorder (ASD) have been reported as
experiencing higher levels of stress and poorer physical health than parents of typically …

Effective treatment of systolic hypertension in elderly patients remains a major therapeutic
challenge. A multicenter, double-blind, randomized controlled trial with sacubitril/valsartan …

The effect of clinic-based intensive hypertension treatment on ambulatory blood pressure
(BP) is unknown. The goal of the SPRINT (Systolic Blood Pressure Intervention Trial) …

Blood pressure (BP) varies over 24 hours. During normal sleep, BP typically decreases by
10% or more. Research suggests that disordered sleep, particularly sleep deprivation and …

Masked hypertension, which is present when in-office normotension translates to out-of-
office hypertension, is present in a surprisingly high percentage of untreated persons and an …

Blood pressure measurement has a long history and a crucial role in clinical medicine.
Manual measurement using a mercury sphygmomanometer and a stethoscope remains the …

The rational management of hypertension (HT) inevitably starts with accurate measurement
of blood pressure (BP). The recently published Systolic Blood Pressure Intervention Trial …