The British Society for Rheumatology guideline for the management of adults with primary Sjögren's Syndrome

EJ Price, S Rauz, AR Tappuni, N Sutcliffe… - …, 2017 - academic.oup.com
Background Primary Sjogren's Syndrome (pSS) is a classic, immune-mediated, condition of
unknown aetiology characterized by focal lymphocytic infiltration of exocrine glands [1] …

Cutaneous and mucosal manifestations of Sjögren's syndrome

E Generali, A Costanzo, C Mainetti, C Selmi - Clinical reviews in allergy & …, 2017 - Springer
Sjögren's syndrome is currently considered an “autoimmune epithelitis,” as exocrine glands,
especially salivary and lacrimal, are progressively destructed by an immune-mediated …

[HTML][HTML] The value of rituximab treatment in primary Sjögren's syndrome

GM Verstappen, JF van Nimwegen, A Vissink… - Clinical …, 2017 - Elsevier
The rationale for B cell depletion therapy with rituximab in primary Sjögren's syndrome relies
upon the well-established role of B cell hyperactivity in immunopathogenesis. In line with …

[HTML][HTML] Chronic autoimmune epithelitis in Sjögren's syndrome and primary biliary cholangitis: a comprehensive review

C Selmi, ME Gershwin - Rheumatology and therapy, 2017 - Springer
Within the spectrum of autoimmune diseases, Sjögren's syndrome and primary biliary
cholangitis are exemplary and can be coined as chronic epithelitis based on their frequent …

Rituximab in the treatment of Sjögren's syndrome: is it the right or wrong drug?

H Bootsma, FGM Kroese… - Arthritis & Rheumatology, 2017 - search.ebscohost.com
The authors focus on the role of B cells in the pathogenesis of a heterogeneous disease
known as Sjögren's syndrome (SS). They discuss the effectiveness of a potent biologic …

[HTML][HTML] B cells are indispensable for a novel mouse model of primary Sjögren's syndrome

J Zheng, Q Huang, R Huang, F Deng, X Yue… - Frontiers in …, 2017 - frontiersin.org
Primary Sjögren's syndrome (pSS) is characterized by a panel of autoantibodies, while it is
not clear whether B cells and autoantibodies play an essential role in pathogenesis of the …

Oral dryness and Sjögren's: an update

PJ Shirlaw, A Khan - British Dental Journal, 2017 - nature.com
Oral dryness is a very common condition presenting to a general dental practitioner or
hospital specialist. The most common cause of oral dryness is drug related, however …

[HTML][HTML] Lymphoma studies in patients with Sjögren's syndrome

L Vasaitis - 2017 - diva-portal.org
Lymphoma studies in patients with Sjögren's syndrome diva-portal.org Digitala
Vetenskapliga Arkivet Simple search Advanced search - Research publicationsAdvanced …

[PDF][PDF] Current views on the pathogenesis of Sjogren's Syndrome

D Lucchesi, M Bombardieri - researchgate.net
Advances in the understanding of pSS pathogenesis have paved the way for clinical trials
with novel biologic agents targeting immune pathways regulating T/B cell interactions and …

Sjögren-Syndrom: Rituximab nicht besser als Placebo

J Lorenz - Aktuelle Rheumatologie, 2017 - thieme-connect.com
Die Therapie des primären Sjögren-Syndrom beruht neben der Gabe von
Immunsuppressiva auf der symptomatischen Behandlung der für diese …