Placental growth factor and pre-eclampsia

K Chau, A Hennessy, A Makris - Journal of human hypertension, 2017 - nature.com
Placental growth factor (PlGF) is an increasingly important molecule in the prediction,
diagnosis and treatment of pre-eclampsia. It has pro-angiogenic effects on the feto-placental …

Preeclampsia: pathogenesis, prevention, and long-term complications

B Jim, SA Karumanchi - Seminars in nephrology, 2017 - Elsevier
Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the …

Matrix metalloproteinases in normal pregnancy and preeclampsia

J Chen, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

[HTML][HTML] Preeclampsia: A review of the pathogenesis and possible management strategies based on its pathophysiological derangements

AAF El-Sayed - Taiwanese Journal of Obstetrics and Gynecology, 2017 - Elsevier
This review is divided into three parts. The first part briefly describes the pathogenesis of
preeclampsia. This is followed by reviewing previously reported management strategies of …

Evidence-based revised view of the pathophysiology of preeclampsia

A Ahmed, H Rezai, S Broadway-Stringer - Hypertension: from basic …, 2017 - Springer
Preeclampsia is a life-threatening vascular disorder of pregnancy due to a failing stressed
placenta. Millions of women risk death to give birth each year and globally each year, almost …

Acute kidney injury in pregnancy-specific disorders

J Prakash, VC Ganiger - Indian journal of nephrology, 2017 - journals.lww.com
The incidence of acute kidney injury in pregnancy (P-AKI) has declined significantly over the
last three decades in developing countries. However, it is still associated with significant …

Placental-specific sFLT-1: role in pre-eclamptic pathophysiology and its translational possibilities for clinical prediction and diagnosis

KR Palmer, S Tong… - MHR: Basic science of …, 2017 - academic.oup.com
Pre-eclampsia is a common obstetric complication globally responsible for a significant
burden of maternal and perinatal morbidity and mortality. Central to its pathophysiology is …

Sex differences in ischaemic stroke: potential cellular mechanisms

A Chauhan, H Moser, LD McCullough - Clinical science, 2017 - portlandpress.com
Stroke remains a leading cause of mortality and disability worldwide. More women than men
have strokes each year, in part because women live longer. Women have poorer functional …

Pathophysiology of hypertension in preeclampsia

N Hariharan, A Shoemaker, S Wagner - Microvascular research, 2017 - Elsevier
Preeclampsia is a hypertensive disorder of pregnancy, classically defined as new-onset
hypertension and proteinuria of at least 300 mg in 24 h. It is among the most common …

Low soluble fms-like tyrosine kinase-1, endoglin, and endothelin-1 levels in women with confirmed or suspected preeclampsia using proton pump inhibitors

L Saleh, R Samantar, IM Garrelds… - …, 2017 - Am Heart Assoc
Patients with preeclampsia display elevated placenta-derived sFlt-1 (soluble Fms-like
tyrosine kinase-1) and endoglin levels and decreased placental growth factor levels. Proton …