[HTML][HTML] Pathophysiology of trauma-induced coagulopathy: disseminated intravascular coagulation with the fibrinolytic phenotype

M Hayakawa - Journal of intensive care, 2017 - Springer
In severe trauma patients, coagulopathy is frequently observed in the acute phase of trauma.
Trauma-induced coagulopathy is coagulopathy caused by the trauma itself. The …

[HTML][HTML] Viscoelastic testing inside and beyond the operating room

L Shen, S Tabaie, N Ivascu - Journal of thoracic disease, 2017 - ncbi.nlm.nih.gov
Hemorrhage is a major contributor to morbidity and mortality during the perioperative period.
Current methods of diagnosing coagulopathy have various limitations including long …

Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label …

P Innerhofer, D Fries, M Mittermayr… - The Lancet …, 2017 - thelancet.com
Background Effective treatment of trauma-induced coagulopathy is important; however, the
optimal therapy is still not known. We aimed to compare the efficacy of first-line therapy …

Change of transfusion and treatment paradigm in major trauma patients

P Stein, A Kaserer, K Sprengel, GA Wanner… - …, 2017 - Wiley Online Library
Trauma promotes traumainduced coagulopathy, which requires urgent treatment with fixed
ratio transfusions of red blood cells, fresh frozen plasma and platelet concentrates, or goal …

Thromboelastometry hypercoagulable profiles and portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma

A Zanetto, M Senzolo, A Vitale, U Cillo, C Radu… - Digestive and Liver …, 2017 - Elsevier
Background Cirrhotic patients with hepatocellular carcinoma (HCC) exhibit
hypercoagulability. Aim We investigated whether thromboelastometry can detect …

[HTML][HTML] Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial

J Winearls, M Wullschleger, E Wake, C Hurn, J Furyk… - Trials, 2017 - Springer
Background Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a
critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen …

Model of trauma-induced coagulopathy including hemodilution, fibrinolysis, acidosis, and hypothermia: impact on blood coagulation and platelet function

B Shenkman, I Budnik, Y Einav… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND Trauma-induced coagulopathy (TIC) is commonly seen among patients with
severe injury. The dynamic process of TIC is characterized by variability of the features of the …

Rotational thromboelastometry can detect factor XIII deficiency and bleeding diathesis in patients with cirrhosis

S Bedreli, JP Sowa, S Malek, S Blomeyer… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Patients with progressive liver disease exhibit complex
coagulation disorders. Factor XIII plays a crucial role in the last steps of haemostasis, and its …

Practical use of thromboelastometry in the management of perioperative coagulopathy and bleeding

B Williams, J McNeil, A Crabbe, KA Tanaka - Transfusion Medicine …, 2017 - Elsevier
Achieving hemostasis after complex cardiovascular and transplant surgical procedures is
one of the greatest challenges anesthesiologists face. Preoperative coagulation …

Point-of-care coagulation monitoring in trauma patients

P Stein, A Kaserer, GH Spahn… - Seminars in thrombosis …, 2017 - thieme-connect.com
Trauma remains one of the major causes of death and disability all over the world.
Uncontrolled blood loss and trauma-induced coagulopathy represent preventable causes of …