Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in
both the endosteum, in the so-called endosteal niche, and close to thin-walled and …

Acute myeloid leukemia and acute lymphoblastic leukemia cells hijack hematopoietic stem
cell (HSC) niches in the bone marrow and become leukemic stem cells (LSCs) at the …

The chemokine SDF-1α plays a critical role in mediating stem cell response to injury and
disease and has specifically been shown to mobilize neural progenitor/stem cells (NPSCs) …

The complex microenvironment that surrounds hematopoietic stem cells (HSCs) in the bone
marrow niche involves different coordinated signaling pathways. The stem cells establish …

Cancer stem cells (CSC) are associated with tumor resistance and are characterized in
gastric cancer (GC). Studies have indicated that Notch and wnt-beta-catenin pathways are …

Generation of functional hematopoietic stem and progenitor cells (HSPCs) from human
pluripotent stem cells (PSCs) has been a long-sought-after goal for use in hematopoietic cell …

Regeneration of tissue structure with the aid of bioactive polymer matrices/composites and
scaffolds for respective applications is one of the emerging areas of biomedical engineering …

The dynamic interactions between leukemic cells and bone marrow (BM) cells in the
leukemia BM microenvironment regulate leukemia stem cell (LSC) properties including …

The clinical application of hematopoietic stem and progenitor cells (HSPCs) has evolved
from a highly experimental stage in the 1980s to a currently clinically established treatment …

Central nervous system (CNS) relapse is a devastating complication that occurs in about 5%
of diffuse large B-cell lymphoma (DLBCL) patients. Currently, there are no predictive …