Cell transplantation therapy for spinal cord injury
Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
Traumatic spinal cord injury
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …
vocational well-being of patients. The demographic of SCIs is shifting such that an …
Myelinogenic plasticity of oligodendrocyte precursor cells following spinal cord contusion injury
Spontaneous remyelination occurs after spinal cord injury (SCI), but the extent of myelin
repair and identity of the cells responsible remain incompletely understood and contentious …
repair and identity of the cells responsible remain incompletely understood and contentious …
Spinal cord injury and related clinical trials
YH Kim, KY Ha, SI Kim - Clinics in orthopedic surgery, 2017 - synapse.koreamed.org
Spinal cord injury (SCI) has been considered an incurable condition and it often causes
devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage …
devastating sequelae. In terms of the pathophysiology of SCI, reducing secondary damage …
Ketogenic metabolism inhibits histone deacetylase (HDAC) and reduces oxidative stress after spinal cord injury in rats
X Wang, X Wu, Q Liu, G Kong, J Zhou, J Jiang, X Wu… - Neuroscience, 2017 - Elsevier
The aim of this study is to investigate the effect of ketogenic metabolism, induced by different
diet interventions, on histone acetylation and its potential antioxidant capacity to injured …
diet interventions, on histone acetylation and its potential antioxidant capacity to injured …
The roles of microRNAs in spinal cord injury
Z Shi, H Zhou, L Lu, X Li, Z Fu, J Liu… - International Journal …, 2017 - Taylor & Francis
Background and purpose: Spinal cord injury (SCI) involves serious damage that can result
in abnormal or absent motor and sensory functions and a disruption of autonomic function …
in abnormal or absent motor and sensory functions and a disruption of autonomic function …
HSYA alleviates secondary neuronal death through attenuating oxidative stress, inflammatory response, and neural apoptosis in SD rat spinal cord compression injury
J Pei, L Fan, K Nan, J Li, X Dang, K Wang - Journal of Neuroinflammation, 2017 - Springer
Abstract Background Hydroxysafflor yellow A (HSYA) is a major active component of yellow
pigment extracted from safflowers; this compound possesses potent neuroprotective effects …
pigment extracted from safflowers; this compound possesses potent neuroprotective effects …
Pathophysiology of traumatic spinal cord injury
S Couillard-Despres, L Bieler, M Vogl - Neurological aspects of spinal …, 2017 - Springer
Traumatic spinal cord injury (SCI) is a drama in two acts. The first part represents the trauma
itself, causing the destruction of neural tissue, ie, the elimination of neuronal and glial cells …
itself, causing the destruction of neural tissue, ie, the elimination of neuronal and glial cells …
An agonist of the protective factor SIRT1 improves functional recovery and promotes neuronal survival by attenuating inflammation after spinal cord injury
Targeting posttraumatic inflammation is crucial for improving locomotor function. SIRT1 has
been shown to play a critical role in disease processes such as hepatic inflammation …
been shown to play a critical role in disease processes such as hepatic inflammation …
Nanomaterial applications for neurological diseases and central nervous system injury
The effectiveness of noninvasive treatment for neurological disease is generally limited by
the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs …
the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs …